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  2. Spironolactone - Wikipedia

    en.wikipedia.org/wiki/Spironolactone

    Spironolactone is used primarily to treat heart failure, edematous conditions such as nephrotic syndrome or ascites in people with liver disease, essential hypertension, low blood levels of potassium, secondary hyperaldosteronism (such as occurs with liver cirrhosis), and Conn's syndrome (primary hyperaldosteronism).

  3. Hair Loss in Women: Everything You Need to Know - AOL

    www.aol.com/hair-loss-women-everything-know...

    Spironolactone is a once-a-day tablet that can stop hair loss from progressing and encourage new hair growth. It’s especially useful for women with hormonal issues like PCOS. It may take six to ...

  4. Does Low Estrogen Cause Hair Loss? - AOL

    www.aol.com/does-low-estrogen-cause-hair...

    Spironolactone stops androgen from binding to receptors, which reduces testosterone and DHT levels and decreases hair loss. Women who are pregnant or trying to get pregnant shouldn’t take ...

  5. Everything I Wish I Knew About Taking Spironolactone for Acne

    www.aol.com/news/everything-know-taking...

    Spironolactone is an acne treatment prescribed by dermatologists. Find out how spironolactone improves the appearance of hormonal acne, side effects, and more. Everything I Wish I Knew About ...

  6. Mineralocorticoid receptor antagonist - Wikipedia

    en.wikipedia.org/wiki/Mineralocorticoid_receptor...

    Eplerenone is a newer drug that was developed as a spironolactone analog with reduced adverse effects. In addition to the y-lactone ring and the substituent on C-7, eplerenone has a 9α,11α-epoxy group. This group is believed to be the reason why eplerenone has a 20-40-fold lower affinity for the mineralocorticoid receptor than spironolactone. [7]

  7. Loop diuretic - Wikipedia

    en.wikipedia.org/wiki/Loop_diuretic

    Loop diuretics may also precipitate kidney failure in patients concurrently taking an NSAID and an ACE inhibitor—the so-called "triple whammy" effect. [19] Because furosemide, torsemide and bumetanide are technically sulfa drugs, there is a theoretical risk that patients sensitive to sulfonamides may be sensitive to these loop diuretics. This ...

  8. The Most Up-To-Date Guide To Women's Hair Loss You'll Read - AOL

    www.aol.com/most-date-guide-womens-hair...

    The reason why it happens is unclear, but it’s suspected that high levels of cortisol, a stress hormone, shortens the growth phase, pushing a greater amount of hair into the shedding phase, adds ...

  9. Pharmacodynamics of spironolactone - Wikipedia

    en.wikipedia.org/wiki/Pharmacodynamics_of...

    Spironolactone has been identified as an inhibitor of NRG1‐ERBB4 signaling. [142] Spironolactone has been found to act as a potent inhibitor of the pannexin 1 channel, and this action appears to be involved in its antihypertensive effects independently of MR antagonism. [143] Spironolactone has been found to block hERG channels. [144]

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