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Serotonin syndrome (SS) is a group of symptoms that may occur with the use of certain serotonergic medications or drugs. [1] The symptoms can range from mild to severe, and are potentially fatal. [ 4 ] [ 5 ] [ 2 ] Symptoms in mild cases include high blood pressure and a fast heart rate ; usually without a fever . [ 2 ]
Early symptoms of serotonin syndrome may include nausea, vomiting, diarrhea, sweating, agitation, confusion, muscle rigidity, dilated pupils, hyperthermia, rigidity, and goose bumps. More severe symptoms include fever, seizures, irregular heartbeat, delirium, and coma. [75] [76] [11] If signs or symptoms arise, discontinue treatment with ...
The intensity of the symptoms of serotonin syndrome vary over a wide spectrum, and the milder forms are seen even at nontoxic levels. [155] It is estimated that 14% of patients experiencing serotonin syndrome overdose on SSRIs; meanwhile the fatality rate is between 2% and 12%. [150] [156] [157]
Seasonal affective disorder (SAD) is a mood disorder subset in which people who typically have normal mental health throughout most of the year exhibit depressive symptoms at the same time each year. [ 1 ] [ 2 ] It is commonly, but not always, associated with the reductions or increases in total daily sunlight hours that occur during the winter ...
Low serotonin levels have been linked to many physical and psychological symptoms, according to Healthline. However, scientists are unsure what actually causes serotonin deficiency.
A withdrawal syndrome may occur if the medication is abruptly stopped or the dose is decreased. [15] Use during pregnancy and breastfeeding is not generally recommended. [16] Vortioxetine's mechanism of action is not entirely understood but is believed to be related to increasing serotonin levels and possibly interacting with certain serotonin ...
According to the Mayo Clinic, some common symptoms include: Difficulty controlling the worry. Feeling nervous, restless, or tense. Trouble concentrating. Forgetfulness.
Serotonin syndrome is typically caused by the use of two or more serotonergic drugs, including SSRIs. [112] Serotonin syndrome is a condition that can range from mild (most common) to deadly. Mild symptoms may consist of increased heart rate , fever , shivering, sweating , dilated pupils , myoclonus (intermittent jerking or twitching), as well ...