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Some lipid-based formulations of theophylline can result in toxic theophylline levels when taken with fatty meals, an effect called dose dumping, but this does not occur with most formulations of theophylline. [13] Theophylline toxicity can be treated with beta blockers. In addition to seizures, tachyarrhythmias are a major concern. [14]
It is a combination drug containing three active ingredients - theophylline, ephedrine, phenobarbital. [2] This medication relaxes the smooth muscle of the airways, making breathing easier. [ 3 ] The common side effects of Tedral include gastrointestinal disturbances , dizziness , headache and lightheadedness .
The effects of theophylline/ephedrine as a performance-enhancing drug in exercise and sports have been studied. [20] [21] Use of theophylline/ephedrine combinations has led to disqualification of elite athletes due to ephedrine being banned in competitive sports. [22]
Viloxazine increased plasma levels of phenytoin by an average of 37%. [21] It also was known to significantly increase plasma levels of theophylline and decrease its clearance from the body, [ 22 ] sometimes resulting in accidental overdose of theophylline .
Zileuton is a minor substrate of CYP1A2, 2C8/9, 3A4, and a weak inhibitor of CYP 1A2. The drug has been shown to increase the serum concentration or effects of theophylline, propranolol, and warfarin, although significant increase in prothrombin time is not obvious. It is advised that the doses of each medication be monitored and/or reduced ...
Medications that lower seizure threshold include the antidepressant and nicotinic antagonist bupropion, the atypical opioid analgesics tramadol and tapentadol, reserpine, [1] theophylline, [2] antibiotics (fluoroquinolones, imipenem, penicillins, cephalosporins, metronidazole, isoniazid) and volatile anesthetics. So can other factors, including:
UBS recommends tech, financials, industrials and utilities stocks going into 2025, citing continued AI growth and pro-business policies under Trump.
An adenosine receptor antagonist is a drug which acts as an antagonist of one or more of the adenosine receptors. [1] The best known are xanthines and their derivatives (natural: caffeine, [2] theophylline, [3] and theobromine; and synthetic: PSB-1901 [4]), but there are also non-xanthine representatives (e.g. ISAM-140, [5] ISAM-R316, [6] etrumadenant, [7] and AZD-4635 [8])