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Head & Shoulders (H&S) is an American brand of anti-dandruff and non-dandruff shampoo produced by parent company Procter & Gamble. The active anti-fungal ingredient in Head & Shoulders is piroctone olamine [ 2 ] or zinc pyrithione , [ 3 ] with some "clinical strength" varieties also containing selenium disulfide .
This is typically oral antifungal medicine for one to three months. ... such as Vanicream Free and Clear Medicated Anti-Dandruff Shampoo or Head and Shoulders Dandruff Shampoo.
Head & Shoulders is a classic for a reason. A tried and true anti-dandruff shampoo, people with dry, itchy scalps rave about it. This particular product in the head and shoulders range is enriched ...
Its antifungal effect is thought to derive from its ability to disrupt membrane transport by blocking the proton pump that energizes the transport mechanism. [16] A study from 2011 showed that antifungal effects of Zinc pyrithione work by copper toxicity mechanism that targets critical iron–sulphur proteins .
While this species does occur naturally on the skin surface of people both with and without dandruff, in 2007, it was discovered that the responsible agent is a scalp specific fungus, Malassezia globosa, [19] that metabolizes triglycerides present in sebum by the expression of lipase, resulting in a lipid byproduct: oleic acid.
The study points towards Malassezia, a fungus commonly found on the human scalp, as the main culprit behind scalp issues. The organism thrives in the oily environment created by accumulated sebum ...
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