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Doxycycline is a broad-spectrum antibiotic of the tetracycline ... Severe liver disease or concomitant use of isotretinoin or other retinoids are contraindications, ...
Tetracyclines are generally used in the treatment of infections of the urinary tract, respiratory tract, and the intestines and are also used in the treatment of chlamydia, especially in patients allergic to β-lactams and macrolides; however, their use for these indications is less popular than it once was due to widespread development of resistance in the causative organisms.
Tetracycline, sold under various brand names, is an antibiotic in the tetracyclines family of medications, used to treat a number of infections, [3] including acne, cholera, brucellosis, plague, malaria, and syphilis. [3]
4 Contraindications. 5 Antibiotic misuse and bacterial resistances. 6 Mechanism of action. ... [61] instead recommending macrolide or doxycycline as first-line agents.
An antibiotic is a type of antimicrobial substance active against bacteria.It is the most important type of antibacterial agent for fighting bacterial infections, and antibiotic medications are widely used in the treatment and prevention of such infections.
Since August 2012, the third-generation cephalosporin, ceftriaxone, is the only recommended treatment for gonorrhea in the United States (in addition to azithromycin or doxycycline for concurrent Chlamydia treatment). Cefixime is no longer recommended as a first-line treatment due to evidence of decreasing susceptibility. [30] Ceftriaxone
Minocycline is also used for other skin infections such as methicillin-resistant Staphylococcus aureus. [23]Although minocycline's broader spectrum of activity, compared with other members of the group, includes activity against Neisseria meningitidis, [24] its use for prophylaxis is no longer recommended because of side effects (dizziness and vertigo).
It is used as a precursor in the industrial synthesis of doxycycline hyclate. [citation needed] It has been found to act as an agonist of the human pregnane X receptor ligand-binding domain and to induce CYP3A4 expression in vitro. [1]
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