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  2. Management of ME/CFS - Wikipedia

    en.wikipedia.org/wiki/Management_of_ME/CFS

    A systematic review found five RCTs to have assessed the effects of immunoglobulin treatment for ME/CFS; [43] of these, two RCTs showed an overall beneficial effect and two RCTs showed some positive results, although in one of the studies this was for physiological effects only. The largest of the RCTs found no effect for the treatment.

  3. Clinical descriptions of ME/CFS - Wikipedia

    en.wikipedia.org/wiki/Clinical_descriptions_of...

    The fatigue must have lasted for 6 months or longer, and be present at least 50% of the time; Other symptoms are possible, such as muscle pain, mood problems, or sleep disturbance; Conditions known to cause severe fatigue and some mental conditions exclude a diagnosis. Post-infectious fatigue syndrome also requires evidence of a prior infection ...

  4. Myalgic encephalomyelitis/chronic fatigue syndrome - Wikipedia

    en.wikipedia.org/.../chronic_fatigue_syndrome

    The term post-infectious fatigue syndrome was initially proposed as a subset of "chronic fatigue syndrome" with a documented triggering infection, but might also be used as a synonym of ME/CFS or as a broader set of fatigue conditions after infection. [26] Many individuals with ME/CFS object to the term chronic fatigue syndrome. They consider ...

  5. Post-exertional malaise - Wikipedia

    en.wikipedia.org/wiki/Post-exertional_malaise

    Post-exertional malaise involves an exacerbation of symptoms, or the appearance of new symptoms, which are often severe enough to impact a person's functioning. [11] While fatigue is often prominent, it is "more than fatigue following a stressor". [6]

  6. Graded exercise therapy - Wikipedia

    en.wikipedia.org/wiki/Graded_exercise_therapy

    Graded exercise therapy (GET) is a programme of physical activity that starts very slowly and gradually increases over time, intended as a treatment for myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS). Most public health bodies, including the CDC and NICE, consider it ineffective, and its safety is disputed.

  7. Malaise - Wikipedia

    en.wikipedia.org/wiki/Malaise

    In medicine, malaise is a feeling of general discomfort, uneasiness or lack of wellbeing and often the first sign of an infection or other disease. [1] The word has existed in French since at least the 12th century. The term is often used figuratively in other contexts, in addition to its meaning as a general state of angst or melancholia.

  8. Fatigue - Wikipedia

    en.wikipedia.org/wiki/Fatigue

    Fatigue in a medical context is used to cover experiences of low energy that are not caused by normal life. [2] [3]A 2021 review proposed a definition for fatigue as a starting point for discussion: "A multi-dimensional phenomenon in which the biophysiological, cognitive, motivational and emotional state of the body is affected resulting in significant impairment of the individual's ability to ...

  9. Likelihood ratios in diagnostic testing - Wikipedia

    en.wikipedia.org/wiki/Likelihood_ratios_in...

    Here "T+" or "T−" denote that the result of the test is positive or negative, respectively. Likewise, "D+" or "D−" denote that the disease is present or absent, respectively. So "true positives" are those that test positive (T+) and have the disease (D+), and "false positives" are those that test positive (T+) but do not have the disease (D ...