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Prolonged use of stimulant laxatives can create drug dependence by damaging the colon's haustral folds, making users less able to move feces through their colon on their own. A study of patients with chronic constipation found that 28% of chronic stimulant laxative users lost haustral folds over the course of one year, while none of the control ...
Macrogol 4000, pharmaceutical quality. Macrogol 3350, often in combination with electrolytes, is used for short-term relief of constipation as well as for long-term use in constipation of various causes, including in multiple sclerosis and Parkinson's disease patients (an often-overlooked non-motor symptom) as well as constipation caused by pharmaceutical drugs such as opioids and ...
However, there may be some short-term side effects, such as diarrhea, nausea, bloating, vomiting, or stomach pain. Normally, these are manageable, but if used for weight loss, the side effects of ...
Common side effects include abdominal bloating and cramps. [3] A potential for electrolyte problems as a result of the diarrhea it produces. [3] No evidence of harm to the fetus has been found when used during pregnancy. [3] It is generally regarded as safe during breastfeeding. [5] It is classified as an osmotic laxative. [6]
They're more likely to result in side effects such as cramping, gas and bloating, so doctors usually don't recommend them for daily use. No one should take laxatives for weight loss, doctors said.
Stimulant laxatives, another type, stimulate the smooth muscle of the bowel to contract, but they often have more side effects, Chang notes. Use a laxative just on occasion when you need it.
Osmotic laxatives such as magnesium citrate work within minutes to eight hours for onset of action, and even then they may not be sufficient to expel the stool. [citation needed] Osmotic laxatives can cause cramping and even severe pain as the patient's attempts to evacuate the contents of the rectum are blocked by the fecal mass.
Side effects are uncommon and typically mild, [1] and may include stomach pain, abdominal cramps or diarrhea, [1] Efficacy decreases with long-term use, and may cause poor bowel function. [9] Serious allergic reactions may occur with the drug. The most severe side effect of docusate, although very rare, is rectal bleeding. [23]