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Prostate-specific antigen (PSA), also known as gamma-seminoprotein or kallikrein-3 (KLK3), P-30 antigen, is a glycoprotein enzyme encoded in humans by the KLK3 gene.PSA is a member of the kallikrein-related peptidase family and is secreted by the epithelial cells of the prostate gland in men and the paraurethral glands in women.
Testosterone promotes prostate cell proliferation, [26] but relatively low levels of serum testosterone are found in patients with BPH. [27] [28] One small study has shown that medical castration lowers the serum and prostate hormone levels unevenly, having less effect on testosterone and dihydrotestosterone levels in the prostate. [29]
Low testosterone is also known to be a contributing factor to erectile dysfunction (ED). ... "High PSA levels may indicate the presence of prostate cancer. However, many other conditions, such as ...
PSA levels between 4 and 10 suggest you could have about a 25 percent chance of prostate cancer, and levels over 10 signal that your chance of having the cancer is more than 50 percent.
As men get older, declining testosterone levels are as inevitable as death and taxes. Around the age of 30, men's T levels start to dwindle by about 1 percent a year.
Prostate cancer is the uncontrolled growth of cells in the prostate, a gland in the male reproductive system below the bladder.Abnormal growth of prostate tissue is usually detected through screening tests, typically blood tests that check for prostate-specific antigen (PSA) levels.
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