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Osteoarthritis is the most common form of arthritis, affecting about 237 million people or 3.3% of the world's population, as of 2015. [4] [12] It becomes more common as people age. [1] Among those over 60 years old, about 10% of males and 18% of females are affected. [2] Osteoarthritis is the cause of about 2% of years lived with disability. [12]
Osteosclerosis is a disorder characterized by abnormal hardening of bone and an elevation in bone density. It may predominantly affect the medullary portion and/or cortex of bone. Plain radiographs are a valuable tool for detecting and classifying osteosclerotic disorders. [1] [2] It can manifest in localized or generalized osteosclerosis.
Bone erosion is the loss of bone from disease processes. Erosive arthritis is joint inflammation ( arthritis ) with bone destruction, and such conditions include rheumatoid arthritis . [ 2 ] Bone erosion is the loss of bone in a certain area, rather than a change in bone density , which is found in osteoporosis .
It can also be a sign of an inflammatory condition called bursitis. ... Since osteoporosis causes loss of bone mineral density, it makes bones more prone to breaking in the event of a hip injury ...
Bone continuously undergoes remodeling by actions of bone resorbing osteoclasts and bone forming osteoblasts. One of the main triggers of bone erosion in the joints in rheumatoid arthritis is inflammation of the synovium , caused in part by the production of pro-inflammatory cytokines and receptor activator of nuclear factor kappa B ligand ...
Grade 3 is the severest form of osteoarthritis, which manifests as severe narrowing of the joint space, large subchondral cyst with productive bone changes that may lead to deformity of the bone components of the joint, while secondary osteoarthritis due to calcium pyrophosphate deposition can be diagnosed when calcification of hyaline ...
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