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  2. Strain (chemistry) - Wikipedia

    en.wikipedia.org/wiki/Strain_(chemistry)

    The strain energy of cyclopropane and cyclobutane are 27.5 and 26.3 kcal mol −1, respectively. [1] Cyclopentane experiences much less strain, mainly due to torsional strain from eclipsed hydrogens: its preferred conformations interconvert by a process called pseudorotation. [4]: 14 Ring strain can be considerably higher in bicyclic systems.

  3. Rotamers - Wikipedia

    en.wikipedia.org/wiki/Rotamers

    a torsion angle between 90° and 150° or −90° and −150° is called anticlinal (ac) a torsion angle between ±150° and 180° is called antiperiplanar (ap), also called anti-or trans-conformation; Torsional strain or "Pitzer strain" refers to resistance to twisting about a bond.

  4. Eclipsed conformation - Wikipedia

    en.wikipedia.org/wiki/Eclipsed_conformation

    A dihedral angle can indicate staggered and eclipsed orientation, but is specifically used to determine the angle between two specific atoms on opposing carbons. Different conformations have unequal energies, creating an energy barrier to bond rotation which is known as torsional strain. In particular, eclipsed conformations tend to have raised ...

  5. Steric effects - Wikipedia

    en.wikipedia.org/wiki/Steric_effects

    Steric hindrance is a consequence of steric effects. Steric hindrance is the slowing of chemical reactions due to steric bulk. It is usually manifested in intermolecular reactions, whereas discussion of steric effects often focus on intramolecular interactions. Steric hindrance is often exploited to control selectivity, such as slowing unwanted ...

  6. Cyclohexane conformation - Wikipedia

    en.wikipedia.org/wiki/Cyclohexane_conformation

    The interaction between the two flagpole hydrogens, in particular, generates steric strain. Torsional strain also exists between the C2–C3 and C5–C6 bonds (carbon number 1 is one of the two on a mirror plane), which are eclipsed — that is, these two bonds are parallel one to the other across a mirror plane. Because of this strain, the ...

  7. Van der Waals strain - Wikipedia

    en.wikipedia.org/wiki/Van_der_Waals_strain

    In molecules whose vibrational mode involves a rotational or pseudorotational mechanism (such as the Berry mechanism or the Bartell mechanism), [2] Van der Waals strain can cause significant differences in potential energy, even between molecules with identical geometry. PF 5, for example, has significantly lower potential energy than PCl 5.

  8. Ring strain - Wikipedia

    en.wikipedia.org/wiki/Ring_strain

    Ring strain theory was first developed by German chemist Adolf von Bayer in 1890. Previously, the only bonds believed to exist were torsional and steric; however, Bayer's theory became based on the interactions between the two strains. Bayer's theory was based on the assumption that ringed compounds were flat.

  9. Taft equation - Wikipedia

    en.wikipedia.org/wiki/Taft_equation

    However, because context will have an effect on steric interactions [7] some E s values can be larger or smaller than expected. For example, the value for phenyl is much larger than that for tert-butyl. When comparing these groups using another measure of steric bulk, axial strain values, the tert-butyl group is larger. [8]