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2. Slipped strand mispairing - Wikipedia

   en.wikipedia.org/wiki/Slipped_strand_mispairing

   Slipped strand mispairing (SSM, also known as replication slippage) is a mutation process which occurs during DNA replication. It involves denaturation and displacement of the DNA strands, resulting in mispairing of the complementary bases. Slipped strand mispairing is one explanation for the origin and evolution of repetitive DNA sequences. [1]

3. Float shifting - Wikipedia

   en.wikipedia.org/wiki/Float_shifting

   Float shifting can reduce clutch wear because it is used so much less (only for starting from a standstill). Conversely, improper engagement of a gear (when the engine and transmission speeds aren't matched) can cause wear on the synchros and lockouts, and damage the gears by physically grinding them together due to a difference in speed.

4. Mismatch loss - Wikipedia

   en.wikipedia.org/wiki/Mismatch_loss

   Any component of the transmission line that has an input and output will contribute to the overall mismatch loss of the system. For example, in mixers mismatch loss occurs when there is an impedance mismatch between the RF port and IF port of the mixer [dubious – discuss]. [4] This is one of the principal reasons for losses in mixers.

5. Frame synchronization - Wikipedia

   en.wikipedia.org/wiki/Frame_synchronization

   If the transmission is temporarily interrupted, or a bit slip event occurs, the receiver must re-synchronize. Frame synchronized PCM stream — telemetry application. The transmitter and the receiver must agree ahead of time on which frame synchronization scheme they will use. Common frame synchronization schemes are: Framing bit

6. Microsatellite instability - Wikipedia

   en.wikipedia.org/wiki/Microsatellite_instability

   It has been shown that MSI-H cancers are dependent on the Werner syndrome helicase (WRN) to repair the DNA secondary structures that are formed by expanded TA microsatellites. [ 9 ] Because of this targeted therapeutic hypothesis, inhibition of WRN has become an area of high interest for the treatment of MSI-H malignancies. [ 21 ]

7. NYT ‘Connections’ Hints and Answers Today, Friday, December 13

   www.aol.com/nyt-connections-hints-answers-today...

   If you've been having trouble with any of the connections or words in Friday's puzzle, you're not alone and these hints should definitely help you out. Plus, I'll reveal the answers further down ...