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Hazardous chemicals present physical and/or health threats to workers in clinical, industrial, and academic laboratories. Laboratory chemicals include cancer-causing agents (carcinogens), toxins (e.g., those affecting the liver, kidney, and nervous system), irritants, corrosives, sensitizers, as well as agents that act on the blood system or damage the lungs, skin, eyes, or mucous membranes.
Risk Group 2 : (moderate individual risk, low community risk) A pathogen that can cause human or animal disease but is unlikely to be a serious hazard to laboratory workers, the community, livestock or the environment. Laboratory exposures may cause serious infection, but effective treatment and preventive measures are available and the risk of ...
A total of 31 people (laboratory workers and their contacts) became sick, seven of whom died. [6] 1971-07-30 1971 Aral smallpox incident: Smallpox Soviet Union The 1971 Aral smallpox incident was the outbreak of viral disease which occurred as a result of a field test at a Soviet biological weapons facility on an island in the Aral Sea. The ...
The USDA animal safety list is located at 9 CFR Subchapter B. [4] Not all select agents require BSL-4 handling, namely select bacteria and toxins, but most select agent viruses do (with the notable exception of SARS-CoV-1 which can be handled in BSL3). Many non-select agent viruses are often handled in BSL-4 according to facility SOPs or when ...
"laboratory personnel have specific training in handling pathogenic agents and are directed by competent scientists." [24] [25] Access to the laboratory is limited when work is being conducted. Certain procedures in which infectious aerosols or splashes may be created are conducted in biological safety cabinets or other physical containment ...
The spot indole test is used to determine if a microbe can deaminate tryptophan to produce indole. This test is performed by saturating a piece of filter paper with Indole Kovacs Reagent and scraping a portion of microbe onto the paper. A color to a pink-red color indicates a positive result while no color change indicates the lack of ...
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From the 1940s to the 1960s, animal bioassays were primarily used to test the toxicity and safety of drugs, food additives, and pesticides. [ 11 ] Beginning in the late 1960s and 1970s, reliance on bioassays increased as public concern for occupational and environmental hazards increased.