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  2. Donepezil - Wikipedia

    en.wikipedia.org/wiki/Donepezil

    Donepezil, sold under the brand name Aricept among others, is a medication used to treat dementia of the Alzheimer's type. [3] [4] [8] It appears to result in a small benefit in mental function and ability to function. [9] Use, however, has not been shown to change the progression of the disease. [10] Treatment should be stopped if no benefit ...

  3. Memantine/donepezil - Wikipedia

    en.wikipedia.org/wiki/Memantine/donepezil

    Memantine/donepezil, sold under the brand name Namzaric among others, is a fixed dose combination medication used for the treatment of dementia of the Alzheimer's type. [1] It contains memantine , as the hydrochloride, a NMDA receptor antagonist ; and donepezil as the hydrochloride, an acetylcholinesterase inhibitor . [ 1 ]

  4. Memantine - Wikipedia

    en.wikipedia.org/wiki/Memantine

    Memantine when added to donepezil in those with moderate-to-severe dementia resulted in "limited improvements" in a 2017 review. [24] The UK National Institute for Clinical Excellence (NICE) issued guidance in 2018 recommending consideration of the combination of memantine with donepezil in those with moderate-to-severe dementia.

  5. List of psychotropic medications - Wikipedia

    en.wikipedia.org/wiki/List_of_psychotropic...

    Desoxyn (methamphetamine hydrochloride) – used to treat attention deficit hyperactivity disorder and exogenous obesity; Dexedrine (dextroamphetamine sulfate) – used to treat attention deficit hyperactivity disorder and narcolepsy

  6. Neuroenhancement - Wikipedia

    en.wikipedia.org/wiki/Neuroenhancement

    [6] [19] The drop-out rates were minimal or non-existent for donepezil, memantine, MPH, and modafinil. [ 6 ] [ 19 ] In the drug trials, participants reported the following adverse reactions to use of donepezil, memantine, MPH, modafinil or caffeine: [ 5 ] gastrointestinal complaints (nausea), headache , dizziness , nightmares , anxiety ...

  7. Tacrine - Wikipedia

    en.wikipedia.org/wiki/Tacrine

    Tacrine was the prototypical cholinesterase inhibitor for the treatment of Alzheimer's disease. William K. Summers received a patent for this use in 1989. [3] [4] [5] Studies found that it may have a small beneficial effect on cognition and other clinical measures, though study data was limited and the clinical relevance of these findings was unclear.

  8. Cholinesterase inhibitor - Wikipedia

    en.wikipedia.org/wiki/Cholinesterase_inhibitor

    Paraoxon and rivastigmine are both acetylcholinesterase inhibitors and butyrylcholinesterase inhibitors. [14] [11] [7]In 2015, the United States Food and Drug Administration's Adverse Event Reporting System database compared rivastigmine to the other ChEI drugs donepezil and galantamine found that rivastigmine was associated with a higher frequency of reports of death as an adverse event.

  9. Hachiro Sugimoto - Wikipedia

    en.wikipedia.org/wiki/Hachiro_Sugimoto

    Sugimoto's research on E2020 (now called Donepezil), an acetylcholinesterase inhibitor, first began at Eisai's Tsukuba Research Laboratories in 1983, [1] because his mother suffered from dementia. [2]