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Phyllodes tumors are part of a group of breast diseases called cellular fibroepithelial lesions. [8] This term incorporates a spectrum of diseases ranging from a benign fibroadenoma to a malignant phyllodes tumor, with numerous variants in between. [14] They are classified by ICD-O, not by MeSH. [14]
A fibroepithelial neoplasm (or tumor) is a biphasic tumor. They consist of epithelial tissue, and stromal or mesenchymal tissue. They may be benign or malignant. [1] Examples include: Brenner tumor of the ovary; Fibroadenoma of the breast; Phyllodes tumor of the breast; Sometimes fibroepithelial polyps (FEPs) of the vulva may be misdiagnosed as ...
Fibroadenoma of the breast is a benign tumor composed of a biplastic proliferation of both stromal and epithelial components. [ 12 ] [ 13 ] This biplasia can be arranged in two growth patterns: pericanalicular (stromal proliferation around epithelial structures) and intracanalicular (stromal proliferation compressing the epithelial structures ...
A hematoxylin and eosin stained slide show a cellular stroma with an innumerable psammoatoid calcifications. By microscopic evaluation, the tumors are composed of a variably cellular stroma make up of spindled to stellate fibroblast-like cells. Within this stroma, are numerous small, rounded, mineralized collagenous ossicles and immature osteoid.
A peripheral ossifying fibroma, also known as ossifying fibrous epulis, is “a gingival nodule which is composed of a cellular fibroblastic connective tissue stroma which is associated with the formation of randomly dispersed foci of mineralised products, which consists of bone, cementum-like tissue, or a dystrophic calcification.
Neoplasia is the medical term used for both benign and malignant tumors, or any abnormal, excessive, uncoordinated, and autonomous cellular or tissue growth. Desmoplastic reaction to breast cancer Desmoplasia refers to growth of dense connective tissue or stroma . [ 2 ]
It appears in the sex cord-stromal tumour group of ovarian neoplasms. Ovary fibromas are most frequent during middle age, and rare in children. Upon gross pathological inspection, ovary fibromas are firm and white or tan. Variants with edema are especially likely to be associated with Meigs' syndrome.
Collagenous fibroma is characterized histopathologically by long, sweeping fascicles of uniformly spindled cells that range in size from moderately to hypercellular. Long, thick-walled arteries exhibiting perivascular stromal edema are seen. [7] Gardner fibroma, nuchal-type fibroma, and desmoid tumor are examples of differential diagnoses. [8]