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Metoprolol is a beta blocker, or an antagonist of the β-adrenergic receptors. It is specifically a selective antagonist of the β 1-adrenergic receptor and has no intrinsic sympathomimetic activity. [37] Metoprolol exerts its effects by blocking the action of certain neurotransmitters, specifically adrenaline and noradrenaline.
This may occur with the class's better known side effect of dry cough (due to decreased breakdown of bradykinin), though there is no clear relationship between the two side effects. The first dose phenomenon in ACEi is reduced and made safer by avoiding diuretics for 24 hours prior to first dose, taking first dose at night (so avoiding falls ...
However, the serotonin receptor antagonism has side effects such as weight gain and impaired movement. [11] Hence, alpha-2 blockers are not used clinically due to its extensive binding. Similar to the alpha-1 blocker, the alpha-2 family will also present the first-dose effect , but it is generally less pronounced compared with the alpha-1 blockers.
Beta-blockers: Propranolol and metoprolol Glucocorticoids: Prednisone and cortisone If your health depends on these medications, ask your doctor if there are alternatives that don't impact weight.
On the flip side, while there isn't scientific evidence of negative effects of this nature at this point, there is some anecdotal evidence linking GLP-1s and a decreased enthusiasm and drive when ...
The doctor can look for potential underlying causes, including dementia, medication effects, or environmental factors, Elhelou says. From there, they can suggest effective ways to help you manage ...
There are several known causes of adrenergic storms; in the United States, cocaine overdose is the leading cause. [16] Any stimulant drug has the capacity to cause this syndrome if taken in sufficient doses, but even non-psychotropic drugs can very rarely provoke a reaction.
Breaking through the noise. Most women going through menopause now grew up in an era when the condition was still considered “rare,” and the signs and symptoms might have been brushed off as ...