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Diltiazem, sold under the brand name Cardizem among others, is a nondihydropyridine calcium channel blocker medication used to treat high blood pressure, angina, and certain heart arrhythmias. [9] It may also be used in hyperthyroidism if beta blockers cannot be used. [ 9 ]
Side effects of these drugs may include but are not limited to: Constipation; Peripheral edema, which can occur in as much as 70% of people receiving calcium channel blocker, is caused by calcium channel blockers' preferential arteriolar or precapillary dilation without commensurate dilation in the venous or postcapillary circulation.
Serious side effects may include low blood pressure and heart failure. [2] Nifedipine is considered safe in pregnancy and breastfeeding. [5] Nifedipine was patented in 1967, and approved for use in the United States in 1981. [2] [6] [7] It is on the World Health Organization's List of Essential Medicines. [8] It is available as a generic ...
Codeine/paracetamol, also called codeine/acetaminophen and co-codamol, is a compound analgesic, comprising codeine phosphate and paracetamol (acetaminophen). Codeine/paracetamol is used for the relief of mild to moderate pain when paracetamol or non-steroidal anti-inflammatory drugs (NSAIDs; such as ibuprofen, aspirin, and naproxen) alone do not sufficiently relieve symptoms.
Ibuprofen was derived from propionic acid by the research arm of Boots Group during the 1960s. [73] The name is derived from the 3 functional groups: isobutyl (ibu) propionic acid (pro) phenyl (fen). [74] Its discovery was the result of research during the 1950s and 1960s to find a safer alternative to aspirin.
Cardiovascular agents generally have narrow therapeutic indices, implying that small differences in dose or blood concentration may give rise to adverse drug reactions. [45] Serious acute toxicity may result from accidental, intentional or iatrogenic overdose. [46] Therefore, patients need to be aware of any unusual and serious side effects.
The side effects for hydrocodone/ibuprofen are a combination of the side effects of the component drugs. Side effects experienced in more than 10% of the population taking the drug include: headache, drowsiness, dizziness, constipation, nausea, and dyspepsia. [5] In the US, the label for hydrocodone/ibuprofen contains a black box warning about ...
Lercanidipine (trade name Zanidip, among others) is an antihypertensive (blood pressure lowering) drug. It belongs to the dihydropyridine class of calcium channel blockers , which work by relaxing and opening the blood vessels allowing the blood to circulate more freely around the body.
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