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The area under the effect curve (AUEC) is an integral of the effect of a drug over time, estimated as a previously-established function of concentration. It was proposed to be used instead of AUC in animal-to-human dose translation, as computer simulation shows that it could cope better with half-life and dosing
Prostaglandin E 2 (PGE 2), also known as dinoprostone, is a naturally occurring prostaglandin with oxytocic properties that is used as a medication. [2] [3] [4] Dinoprostone is used in labor induction, bleeding after delivery, termination of pregnancy, and in newborn babies to keep the ductus arteriosus open.
To ensure that the drug taker who has poor absorption is dosed appropriately, the bottom value of the deviation range is employed to represent real bioavailability and to calculate the drug dose needed for the drug taker to achieve systemic concentrations similar to the intravenous formulation. [4]
The ED 95 is the dose required to achieve the desired effect in 95% of the population. In anaesthesia, the term ED 95 is also used when referring to the pharmacology of neuromuscular blocking drugs. In this context, it is the dose which will cause 95% depression of the height of a single muscle twitch, in half of the population.
However, the column height of the first bin (e.g., [0, 1] Gy) represents the volume of structure receiving a dose greater than or equal to that dose. [5] The column height of the second bin (e.g., (1, 2] Gy) represents the volume of structure receiving greater than or equal to that dose, etc.
Billie Lourd is feeling "griefful" on the eighth anniversary of mom Carrie Fisher's death, the actor shared in a moving tribute. On Dec. 27, Lourd, 32, took to Instagram to share a throwback photo ...
Fitness doesn't take a holiday in Mark Wahlberg's house. The Flight Risk actor, 52, showed off his fit physique on Instagram in the early-morning hours of Thursday, Dec. 26, after celebrating ...
Among the 14 people killed in the New Orleans attack: a warehouse manager, an account executive, an aspiring nurse and two loving parents.
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