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Diphenhydramine is a potent antimuscarinic (a competitive antagonist of muscarinic acetylcholine receptors) and, as such, at high doses can cause anticholinergic syndrome. [68] The utility of diphenhydramine as an antiparkinson agent is the result of its blocking properties on the muscarinic acetylcholine receptors in the brain.
Structural heart disease, such as heart failure, myocardial infarction, and left ventricular hypertrophy, are also risk factors. Diuretic-induced hypokalemia and/or hypomagnesemia taken for heart failure can induce proarrthymia. The ischemia that results from myocardial infarctions also induce QT prolongation. [citation needed]
When the breastbone (sternum) and attached ribs are sunken in enough to put excess pressure on the heart and lungs which can cause tachycardia and skipped beats. Palpitations can occur during times of catecholamine excess, such as during exercise or at times of stress. [1]
“When the heart doesn't beat properly, it can't pump blood effectively. When this happens, the lungs, brain and all other organs can't work properly and may shut down or be damaged,” Dr. Mehta ...
And doctors are widely taught that caffeine can cause these heart disturbances. To check, Marcus and colleagues examined 1,388 people, with an average age of 72, taking part in a larger heart study.
Heart palpitations and arrhythmias, hypotension, nausea, vomiting, abdominal pain, respiratory system paralysis, death [4] [5] Aloe vera juice medicinal aloe Aloe vera "abdominal pain, diarrhea, potentially carcinogenic, with others can potentiate cardiac glycosides and antiarrhythmic agents" [3] Anthranoid laxatives
Here's More Evidence That Common Drugs May Cause Cognition Issues. If you've ever popped a Benadryl or two to sleep through a long flight (or even just a regular night), you can pretty much count ...
An FAA report found that between 2012 and 2016, diphenhydramine was the most common pharmaceutical known to cause impairment detected in post-mortem toxicology tests performed on someone who may have been in charge of the aircraft at the time of a fatal plane crash, specifically naming both Benadryl and Sominex. [65]