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Cells generate and maintain mechanical forces within their environment as a part of their physiology. Cell biomechanics deals with how mRNA, protein production, and gene expression is affected by said environment and with mechanical properties of isolated molecules or interaction of proteins that make up molecular motors. [1]
Cell mechanics is a sub-field of biophysics that focuses on the mechanical properties and behavior of living cells and how it relates to cell function. [1] It encompasses aspects of cell biophysics , biomechanics , soft matter physics and rheology , mechanobiology and cell biology .
In 1903, Nikolai K. Koltsov proposed that the shape of cells was determined by a network of tubules that he termed the cytoskeleton. The concept of a protein mosaic that dynamically coordinated cytoplasmic biochemistry was proposed by Rudolph Peters in 1929 [12] while the term (cytosquelette, in French) was first introduced by French embryologist Paul Wintrebert in 1931.
Mechanobiology is an emerging field of science at the interface of biology, engineering, chemistry and physics. It focuses on how physical forces and changes in the mechanical properties of cells and tissues contribute to development, cell differentiation, physiology, and disease.
In cell biology, the spindle apparatus is the cytoskeletal structure of eukaryotic cells that forms during cell division to separate sister chromatids between daughter cells. It is referred to as the mitotic spindle during mitosis , a process that produces genetically identical daughter cells, or the meiotic spindle during meiosis , a process ...
In Chara coralina, cells can grow up to 10 cm long and 1 mm in diameter. [8] The diameter of the vacuole can occupy around 80% of the cell's diameter. [11] Thus for a 1 mm diameter cell, the vacuole can have a diameter of 0.8 mm, leaving only a path width of about 0.1 mm around the vacuole for cytoplasm to flow.
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The cell is the fundamental unit of structure and function in all living organisms. [14] The activity of an organism depends on the total activity of independent cells. [15] Energy flow (metabolism and biochemistry) occurs within cells. Cells contain DNA which is found specifically in the chromosome and RNA found in the cell nucleus and ...