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Trichophyton rubrum is a dermatophytic fungus in the phylum Ascomycota. It is an exclusively clonal, [ 2 ] anthropophilic saprotroph that colonizes the upper layers of dead skin, and is the most common cause of athlete's foot , fungal infection of nail, jock itch , and ringworm worldwide. [ 3 ]
Two feet-one hand syndrome (TFOHS), is a long-term fungal condition where athlete's foot or fungal toe nail infections in both feet is associated with tinea manuum in one hand. [ 3 ] [ 7 ] Often the feet are affected for several years before symptoms of a diffuse scaling rash on the palm of one hand appear, which is when most affected people ...
Ciclopirox is indicated as topical treatment in immunocompetent people with mild to moderate onychomycosis of fingernails and toenails without lunula involvement, due to Trichophyton rubrum, [3]; and for the treatment of seborrheic dermatitis. [4]
Trichophyton rubrum is the most common dermatophyte involved in onychomycosis. Other dermatophytes that may be involved are T. interdigitale, Epidermophyton floccosum, Tricholosporum violaceum, Microsporum gypseum, T. tonsurans, and T. soudanense.
A 2002 study looking at 445 samples of dermatophytes in patients in Goiânia, Brazil found the most prevalent type to be Trichophyton rubrum (49.4%), followed by Trichophyton mentagrophytes (30.8%), and Microsporum canis (12.6%). [36]
When both hands are affected, the rash looks different on each hand, with palmer creases appearing whitish if the infection has been present for a long time. [5] It can be itchy and look slightly raised. [5] Nails may also be affected. [5] The most common cause is Trichophyton rubrum. [2]
Onychomycosis, also known as tinea unguium, is a contagious infection of the nail caused by the same fungal organisms which cause ringworm of the skin (Trichophyton rubrum or T. mentagrophytes, rarely other trichophyton species or Epidermophyton floccosum [1]).
Trichophyton is a genus of fungi, which includes the parasitic varieties that cause tinea, including athlete's foot, ringworm, jock itch, and similar infections of the nail, beard, skin and scalp. Trichophyton fungi are molds characterized by the development of both smooth-walled macro- and microconidia .