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As one would expect from the name, individuals affected by this disorder have difficulty managing and grooming their hair. Affected individuals usually possess blonde or silver hair that may be present at birth or develop over time. [1] The hair is wiry, frizzy, and stands straight out from the scalp. [1] It is often dry but not fragile or ...
The pattern of hair growth in generalized prepubertal hypertrichosis predominates the face, back, and limbs. [6] Importantly, this is unique from excessive hair growth patterns in hirsutism. [6] Hypertrichosis itself is benign, but presents a cosmetic issue that may lead to psychosocial problems.
The diagnosis of HAIR-AN is based on identifying the symptoms and correlating them to the known risk factors. [10] The severity of hirsutism which accompanies the HAIR-AN syndrome has been found to correlate to the activity of the stromal ovarian cells, as they are overstimulated by elevated insulin levels. [7]
Acquired hypertrichosis lanuginosa is characterized by rapid growth of lanugo hair, particularly on the face. [12] [13] Hair also appears on the trunk and armpits, while palms and soles are unaffected. [13] The excess hair is commonly referred to as malignant down. [13] This hair is very fine and unpigmented. [13] Generalized hypertrichosis
The skin may be lightly pigmented. Skin sustaining injury may grow back permanently hypo-pigmented. In some cases, red or brown pigmentation may be present. Skin can be prone to rashes or infections and can be thick over the palms and soles. Care must be taken to prevent cracking, bleeding, and infection.
Ferrets with Waardenburg syndrome have a small white stripe along the top or back of the head and sometimes down the back of the neck (known as a "blaze" coat pattern), or a solid-white head from nose to shoulders (known as a "panda" coat pattern). Affected ferrets often have a very slightly flatter skull and wider-set eyes than healthy ferrets.
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Canities subita, also called Marie Antoinette syndrome or Thomas More syndrome, is an alleged condition of hair turning white overnight due to stress or trauma. [1] The trivial names come from specific cases in history including that of Queen Marie Antoinette of France whose hair was noted as having turned stark white overnight after her capture following the ill-fated flight to Varennes ...