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A circular chromosome is a chromosome in bacteria, archaea, mitochondria, and chloroplasts, in the form of a molecule of circular DNA, unlike the linear chromosome of most eukaryotes. Most prokaryote chromosomes contain a circular DNA molecule. This has the major advantage of having no free ends to the DNA.
Extrachromosomal circular DNA (eccDNA) is a type of double-stranded circular DNA structure that was first discovered in 1964 by Alix Bassel and Yasuo Hotta. [1] In contrast to previously identified circular DNA structures (e.g., bacterial plasmids, mitochondrial DNA, circular bacterial chromosomes, or chloroplast DNA), eccDNA are circular DNA found in the eukaryotic nuclei of plant and animal ...
Circular DNA is DNA that forms a closed loop and has no ends. Examples include: Plasmids, mobile genetic elements; cccDNA, formed by some viruses inside cell nuclei; Circular bacterial chromosomes; Mitochondrial DNA (mtDNA) Chloroplast DNA (cpDNA), and that of other plastids; Extrachromosomal circular DNA (eccDNA)
Mitochondrial DNA (mtDNA) was found in the malaria parasite. [48] There are two forms of extrachromosomal DNA found in the malaria parasites. One of these is 6-kb linear DNA and the second is 35-kb circular DNA. These DNA molecules have been researched as potential nucleotide target sites for antibiotics. [49]
In many bacteria, the chromosome is a single covalently closed (circular) double-stranded DNA molecule that encodes the genetic information in a haploid form. The size of the DNA varies from 500,000 to several million base pairs (bp) encoding from 500 to several thousand genes depending on the organism. [2]
The 154 kb chloroplast DNA map of a model flowering plant (Arabidopsis thaliana: Brassicaceae) showing genes and inverted repeats. Chloroplast DNAs are circular, and are typically 120,000–170,000 base pairs long. [7] [8] [9] They can have a contour length of around 30–60 micrometers, and have a mass of about 80–130 million daltons. [10]
The first type is a circular genome that has introns (type 2) and may range from 19 to 1000 kbp in length. The second genome type is a circular genome (about 20–1000 kbp) that also has a plasmid-like structure (1 kb) (type 3). The final genome type found in plants and fungi is a linear genome made up of homogeneous DNA molecules (type 5).
Neighbouring plant cells are therefore separated by a pair of cell walls and the intervening middle lamella, forming an extracellular domain known as the apoplast. Although cell walls are permeable to small soluble proteins and other solutes , plasmodesmata enable direct, regulated, symplastic transport of substances between cells.