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The disorder can cause heart abnormalities and seizures if the amount of methemoglobin in the blood exceeds 20 percent, but at levels between 10 and 20 percent it can cause blue skin without other symptoms. Most of the Fugates lived long and healthy lives. The "bluest" of the blue Fugates, Luna Stacy, had 13 children and lived to age 84. [6]
The Fugates, a family that lived in the hills of Kentucky in the US, had the hereditary form. They are known as the "Blue Fugates". [ 30 ] Martin Fugate and Elizabeth Smith, who had married and settled near Hazard, Kentucky , around 1800, were both carriers of the recessive methemoglobinemia (met-H) gene, as was a nearby clan with whom the ...
It turns out, even a very short bout of exercise can make a major impact on women's heart health. According to a 2024 study in the British Journal of Sports Medicine , 3.4 minutes of intense ...
Cardiovascular disease in women is an integral area of research in the ongoing studies of women's health. Cardiovascular disease (CVD) is an umbrella term for a wide range of diseases affecting the heart and blood vessels, including but not limited to, coronary artery disease, stroke, cardiomyopathy, myocardial infarctions, and aortic aneurysms.
“Heart disease is very common and occurs in 12.1 percent of the U.S. population,” says Kevin J. Croce, MD, a cardiologist at Brigham and Women’s Hospital and an assistant professor of ...
Heart health is a long-time pain point for Americans—physically and emotionally. Heart disease is the leading cause of death in the U.S., and that number crosses sex, racial and ethnic lines ...
The structure of cytochrome b5 reductase, the enzyme that converts methemoglobin to hemoglobin. [1]Methemoglobin (British: methaemoglobin, shortened MetHb) (pronounced "met-hemoglobin") is a hemoglobin in the form of metalloprotein, in which the iron in the heme group is in the Fe 3+ state, not the Fe 2+ of normal hemoglobin.
Furthermore, mongolian spots, large birthmarks, and the consumption of food products with blue or purple dyes can also result in the bluish skin tissue discoloration and may be mistaken for cyanosis. [ 2 ] [ 3 ] Appropriate physical examination and history taking is a crucial part to diagnose cyanosis.