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[1] [2] [3] It is specifically comparing three to four 100 μg/day estradiol patches (FemSeven or Progynova TS) against goserelin implants in approximately 2,200 men with prostate cancer. [1] [4] The study was started in March 2006 and is estimated for completion in August 2021, with additional reports expected in 2023 and 2024.
AOH1996 is an experimental anticancer medication which acts as a small molecule inhibitor of proliferating cell nuclear antigen (PCNA) and is in Phase I clinical trials at City of Hope as of August 2023 for the treatment of solid tumors. [1] [2] [3] [4]
The safety and efficacy of piflufolastat F-18 were evaluated in two prospective clinical trials (trial 1/NCT02981368 and trial 2/NCT03739684) with a total of 593 men with prostate cancer who each received one injection of piflufolastat F-18.
Its shares hit a record high of $41.22, after declining 18.53% in 2023 and were on track to add more than $1.2 billion to its market capitalization, if gains hold.
In 2006, scientists from Purdue University designed a targeting ligand that bound with high affinity and specificity to PSMA on prostate cancer cells and patented [13] [14] its ability to target attached radionuclides such as 177 Lu, 99m Tc, 68 Ga, etc. to prostate cancers. The patents were licensed to Endocyte in 2007.
The programme consisted of three large randomized, double-blind, placebo-controlled trials in which a total of 8,113 men with localized or locally advanced prostate cancer were treated with 150 mg/day bicalutamide plus standard care (watchful waiting, radical prostatectomy, or radiation therapy) (n=4052) or given placebo (standard care alone ...
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