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  2. Idiopathic granulomatous hepatitis - Wikipedia

    en.wikipedia.org/wiki/Idiopathic_granulomatous...

    Idiopathic granulomatous hepatitis is a rare medical condition characterized by granulomas in the liver, recurrent fever, myalgia, and fatigue. The condition is not a true hepatitis , and some experts believe it is a variant of sarcoidosis .

  3. Granuloma - Wikipedia

    en.wikipedia.org/wiki/Granuloma

    Other common sites of involvement include the liver, spleen, skin, and eyes. The granulomas of sarcoidosis are similar to those of tuberculosis and other infectious granulomatous diseases. In most cases of sarcoidosis, though, the granulomas do not contain necrosis and are surrounded by concentric scar tissue .

  4. Hepatotoxicity - Wikipedia

    en.wikipedia.org/wiki/Hepatotoxicity

    Drug-induced hepatic granulomas are usually associated with granulomas in other tissues and patients typically have features of systemic vasculitis and hypersensitivity. More than 50 drugs have been implicated. Causes: Allopurinol, phenytoin, isoniazid, quinine, penicillin, quinidine

  5. Sarcoidosis - Wikipedia

    en.wikipedia.org/wiki/Sarcoidosis

    Around 70% of people have granulomas in their livers, although only in about 20–30% of cases, liver function test anomalies reflecting this fact are seen. [20] [28] About 5–15% of patients exhibit hepatomegaly. [22] Only 5–30% of cases of liver involvement are symptomatic. [68]

  6. Granulomatosis with polyangiitis - Wikipedia

    en.wikipedia.org/wiki/Granulomatosis_with...

    These granulomas are the main reason for the name granulomatosis with polyangiitis, although it is not an essential feature. Nevertheless, necrotizing granulomas are a hallmark of this disease. However, many biopsies can be nonspecific and 50% provide too little information for the diagnosis of GPA. [12]

  7. Gumma (pathology) - Wikipedia

    en.wikipedia.org/wiki/Gumma_(pathology)

    Gummas have a firm, necrotic center surrounded by inflamed tissue, which forms an amorphous proteinaceous mass. The center may become partly hyalinized.These central regions begin to die through coagulative necrosis, though they also retain some of the structural characteristics of previously normal tissues, enabling a distinction from the granulomas of tuberculosis where caseous necrosis ...

  8. Schistosomiasis - Wikipedia

    en.wikipedia.org/wiki/Schistosomiasis

    This condition occurs mainly in children and adolescents due to early immune reaction to eggs trapped within the periportal and presinusoidal spaces of the liver creating numerous granulomas. [19] Liver function is not affected, and the severity of liver and spleen enlargement is correlated to the intensity of the infection. [19]

  9. Autoimmune hepatitis - Wikipedia

    en.wikipedia.org/wiki/Autoimmune_hepatitis

    Autoimmune hepatitis, formerly known as lupoid hepatitis, plasma cell hepatitis, or autoimmune chronic active hepatitis, is a chronic, autoimmune disease of the liver that occurs when the body's immune system attacks liver cells, causing the liver to be inflamed.