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Various risk factors contribute to VTE, including genetic and environmental factors, though many with multiple risk factors never develop it. [57] [58] Acquired risk factors include the strong risk factor of older age, [5] which alters blood composition to favor clotting. [59] Previous VTE, particularly unprovoked VTE, is a strong risk factor. [60]
Deep vein thrombosis may require thrombolysis if there is a significant risk of post-thrombotic syndrome. [42] Thrombolysis may be administered by intravenous catheter directly into the clot ("catheter-directed thrombolysis"); this requires a lower dose of the medication and may carry a lower bleeding risk but evidence for its benefit is limited.
Deep vein thrombosis (DVT) is the formation of a blood clot within a deep vein. It most commonly affects leg veins, such as the femoral vein. Three factors are important in the formation of a blood clot within a deep vein—these are: the rate of blood flow, the thickness of the blood and; qualities of the vessel wall.
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A right-sided acute deep vein thrombosis (to the left in the image). The leg is swollen and red due to venous outflow obstruction. The most common conditions associated with thrombophilia are deep vein thrombosis (DVT) and pulmonary embolism (PE), which are referred to collectively as venous thromboembolism (VTE). DVT usually occurs in the legs ...
When physicians find a DVT in the clinical history of their patients, a postthrombotic syndrome is possible if the patients have suggestive symptoms. Ultrasonography for deep venous thrombosis must be performed to evaluate the situation: the degree of obstruction by clots, the location of these clots, and the detection of deep and/or ...
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