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Muscle weakness is a lack of muscle strength. Its causes are many and can be divided into conditions that have either true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy.
Limb girdle muscular dystrophies (LGMD) as defined by the European Neuromuscular Centre in 2018. [1] [2] They are named by the following system: LGMD, recessive or dominant inheritance (R or D), order of discovery (number), affected protein. [1] LGMD D1 DNAJB6-related; LGMD D2 TNP03-related; LGMD D3 HNRNPDL-related; LGMD D4 calpain3-related
This is a list of major and frequently observed neurological disorders (e.g., Alzheimer's disease), symptoms (e.g., back pain), signs (e.g., aphasia) and syndromes (e.g., Aicardi syndrome). There is disagreement over the definitions and criteria used to delineate various disorders and whether some of these conditions should be classified as ...
The causes are many and can be divided into conditions that have true or perceived muscle weakness. True muscle weakness is a primary symptom of a variety of skeletal muscle diseases, including muscular dystrophy and inflammatory myopathy. It occurs in neuromuscular junction disorders, such as myasthenia gravis. [citation needed]
Muscular dystrophies, including Duchenne's and Becker's, are a large group of diseases, many of them hereditary or resulting from genetic mutations, where the muscle integrity is disrupted, they lead to progressive loss of strength and decreased life span. [17] Further causes of neuromuscular diseases are: Polymyositis. Inflammatory muscle ...
Diseases and disorders DAS Developmental apraxia of speech: DBA Diamond–Blackfan anemia: DBMD Duchenne–Becker muscular dystrophy DD Developmental disability: DEF Deaf: DF Dengue fever: DH Developmentally handicapped: DHF Dengue hemorrhagic fever: DHF Diastolic heart failure: DHPR Dihydropteridine reductase deficiency: DI Diabetes insipidus: DIC
Cancer-related fatigue; CANDLE syndrome; Canine epileptoid cramping syndrome; Cannabinoid hyperemesis syndrome (CHS) Cantú syndrome; Capgras delusion; Capgras syndrome; Capillary leak syndrome; Caplan's syndrome; Carcinoid syndrome; Cardiac syndrome X; Cardiofaciocutaneous syndrome; Cardiorenal syndrome; Cardiovascular syndrome; Carney complex ...
There are two main causes of muscle fatigue: the limitations of a nerve’s ability to generate a sustained signal (neural fatigue); and the reduced ability of the muscle fiber to contract (metabolic fatigue). Muscle fatigue is not the same as muscle weakness, though weakness is an initial symptom.