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The protein encoded by this gene is highly similar to the gene product of Schizosaccharomyces pombe rad17, a cell cycle checkpoint gene required for cell cycle arrest and DNA damage repair in response to DNA damage. This protein shares strong similarity with DNA replication factor C (RFC), and can form a complex with RFCs.
Cycle (cyc) is a gene in Drosophila melanogaster that encodes the CYCLE protein (CYC). The Cycle gene ( c yc) is expressed in a variety of cell types in a circadian manner. It is involved in controlling both the sleep-wake cycle and circadian regulation of gene expression by promoting transcription in a negative feedback mechanism.
8697 52563 Ensembl ENSG00000094880 ENSMUSG00000024370 UniProt Q9UJX2 Q8BGZ4 RefSeq (mRNA) NM_004661 NM_178347 RefSeq (protein) NP_004652 NP_848124 Location (UCSC) Chr 5: 138.19 – 138.21 Mb Chr 18: 34.76 – 34.78 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cell division cycle 23 homolog (S. cerevisiae), also known as CDC23, is a protein that, in humans, is encoded by the CDC23 ...
66214 Ensembl ENSG00000102760 ENSMUSG00000022018 UniProt Q9H4X1 Q9DBX1 RefSeq (mRNA) NM_014059 NM_025427 RefSeq (protein) NP_054778 NP_079703 Location (UCSC) Chr 13: 41.46 – 41.47 Mb Chr 14: 79.53 – 79.54 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Regulator of cell cycle RGCC (RGCC) also known as response gene to complement 32 protein (RGC-32) is a protein that in humans is ...
This gene encodes a component protein of the APC complex, which is composed of eight proteins and functions as a protein ubiquitin ligase. The APC complex is a cyclin degradation system that governs exit from mitosis. Each component protein of the APC complex is highly conserved among eukaryotic organisms.
19355 Ensembl ENSG00000113456 ENSMUSG00000022248 UniProt O60671 Q9QWZ1 RefSeq (mRNA) NM_001033673 NM_002853 NM_133282 NM_133377 NM_001289447 NM_001289448 NM_011232 RefSeq (protein) NP_002844 NP_001276376 NP_001276377 NP_035362 Location (UCSC) Chr 5: 34.91 – 34.92 Mb Chr 15: 10.49 – 10.5 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse Cell cycle checkpoint protein RAD1 is a ...
This gene is highly conserved during evolution and it plays a key role in the regulation of cell division. The encoded protein is a tyrosine phosphatase and belongs to the Cdc25 phosphatase family. It directs dephosphorylation of cyclin B-bound CDC2 (CDK1) and triggers entry into mitosis.
894 12444 Ensembl ENSG00000118971 ENSMUSG00000000184 UniProt P30279 P30280 RefSeq (mRNA) NM_001759 NM_009829 RefSeq (protein) NP_001750 NP_033959 Location (UCSC) Chr 12: 4.27 – 4.31 Mb Chr 6: 127.13 – 127.15 Mb PubMed search Wikidata View/Edit Human View/Edit Mouse G1/S-specific cyclin-D2 is a protein that in humans is encoded by the CCND2 gene. Function The protein encoded by this gene ...