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Contrast CT, or contrast-enhanced computed tomography (CECT), is X-ray computed tomography (CT) using radiocontrast. Radiocontrasts for X-ray CT are generally iodine-based types . [ 1 ] This is useful to highlight structures such as blood vessels that otherwise would be difficult to delineate from their surroundings.
Relatively common side effects include vomiting, diarrhea, and skin redness. [4] Other side effects include itchiness, kidney problems, low blood pressure, and allergic reactions. [1] It is not recommended in people who have an iodine allergy. [1] Diatrizoate is an iodinated ionic radiocontrast agent with high osmolality. [2]
Contrast CT of a patient with brain metastases from breast cancer, before (left) and after (right) injection of iodinated contrast.. Iodinated contrast is a form of water-soluble, intravenous radiocontrast agent containing iodine, which enhances the visibility of vascular structures and organs during radiographic procedures.
Iohexol, sold under the trade name Omnipaque among others, is a contrast agent used for X-ray imaging. [4] This includes when visualizing arteries, veins, ventricles of the brain, the urinary system, and joints, as well as during computed tomography (CT scan). [4] It is given by mouth, injection into a vein, or into a body cavity. [5]
Iobitridol is generally well tolerated. [5] The only side effect observed in more than 1% of patients is nausea.Rare side effects (in fewer than 1 per 10.000 people) include anaphylaxis (severe allergic reactions), circulatory collapse, kidney failure, thyroid-related effects, and skin reactions such as Stevens–Johnson syndrome.
Iodinated contrast contains iodine.It is the main type of radiocontrast used for intravenous administration.Iodine has a particular advantage as a contrast agent for radiography because its innermost electron ("k-shell") binding energy is 33.2 keV, similar to the average energy of x-rays used in diagnostic radiography.
As with other iodinated contrast agents there are concerns regarding safety, particularly relating to effects on renal function and allergic type reaction. Early generations of intravenous (IV) contrast carried considerable nephrotoxicity, necessitating continual assessment of renal function. IV and PO (per os, by mouth) fluids are encouraged ...
The most common reactions from these agents are mild, including nausea, vomiting, and an itching rash. Severe life-threatening reactions may rarely occur. [174] Overall reactions occur in 1 to 3% with nonionic contrast and 4 to 12% of people with ionic contrast. [175] Skin rashes may appear within a week to 3% of people. [174]