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Plasmapheresis (from the Greek πλάσμα, plasma, something molded, and ἀφαίρεσις aphairesis, taking away) is the removal, treatment, and return or exchange of blood plasma or components thereof from and to the blood circulation.
Apheresis (ἀφαίρεσις (aphairesis, "a taking away")) is a medical technology in which the blood of a person is passed through an apparatus that separates out one particular constituent and returns the remainder to the circulation. It is thus an extracorporeal therapy. One of the uses of apheresis is for collecting hematopoetic stem ...
In medicine, photopheresis (aka extracorporeal photopheresis or ECP) [1] is a form of apheresis and photodynamic therapy in which blood is subject to apheresis to separate buffy coat (WBC + platelets) from whole blood, chemically treated with 8-methoxypsoralen (instilled into a collection bag or given per os in advance), exposed to ultraviolet light (UVA), and then returned to the patient. [2]
During apheresis treatments adverse events such as anemia, citrate toxicity, central venous catheter safety and infections are notable. [2] [3] [8]Anemia: Anemia is related to numerous and/or consecutive treatments and/or large extracorporeal circuits that reduces the hemoglobin levels in pediatric patients.
Platelets collected by using apheresis at an American Red Cross donation center. Not all platelet transfusions use platelets collected by automated apheresis. The platelets can also be separated from donations of whole blood collected in a traditional blood donation, but there are several advantages to separating the platelets at the time of collection.
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In the United States it refers to the fluid portion of one unit of whole blood that has been centrifuged, separated, and frozen solid at −18 °C (0 °F) or colder within eight hours of collection from whole blood donation or was otherwise collected via apheresis device. [9] The phrase "FFP" is often used to mean any transfused plasma product.
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