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[11] [12] Praziquantel is also effective against Echinococcus multilocularis. [11] Schistosomiasis caused by trematodes of the genus Schistosoma: [13] As of 2005, praziquantel is the primary treatment for human schistosomiasis, for which it is usually effective in a single dose. [14] Clonorchiasis brought on by the Chinese liver fluke ...
[5] [6] It kills adult fleas (Ctenocephalides felis) and is indicated for the treatment and prevention of flea infestations and the treatment and control of Ixodes scapularis (black-legged tick) and Amblyomma americanum (lone star tick) infestations for one month in cats and kittens eight weeks of age and older, and weighing 1.8 pounds (0.82 kg ...
The best way to treat this condition in humans is with surgery, as most drug treatments are unsuccessful at getting rid of the larval stages. [3] In animals, infections with Spirometra species can be treated with praziquantel at 30-35 mg/kg, PO of SQ, for 2 consecutive days. [12] Mebendazole at 11 mg/kg, PO, has also been successful.
The drug is FDA-approved for prevention of heartworm in dogs and cats, [4] although it is less potent against heartworms than ivermectin. [citation needed] The substance is often combined with other parasiticides to achieve a broader spectrum of action. Such products include: [citation needed] Milbemax and Interceptor Plus (with praziquantel)
Treatment of opisthorchiasis is usually accomplished with praziquantel. A single dose of praziquantel of 40 mg/kg is effective against opisthorchiasis (and also against schistosomiasis). [8] Despite the efficacy of this compound, the lack of acquired immunity to infection predisposes humans to reinfection in endemic regions.
Emodepside is an anthelmintic drug that is effective against a number of gastrointestinal nematodes, is licensed for use in cats [1] and belongs to the class of drugs known as the octadepsipeptides, [2] a relatively new class of anthelmintic (research into these compounds began in the early 1990s), [3] which are suspected to achieve their anti-parasitic effect by a novel mechanism of action ...
One treatment for sparganosis is praziquantel, administered at a dose of 120 to 150 mg/kg body weight over 2 days; however, praziquantel has had limited success. In general, infestation by one or a few sparganum larvae is often best treated by surgical removal. [1] [9]
Praziquantel causes immobilized contraction of the worm, such that it can no longer grasp the intestinal walls, and can be eliminated from the body. Three 2-g doses of niclosamide or two 50 mg/kg doses of bithionol have also been effective when praziquantel was either not available or treatment was refused. [2]
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