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Let's look at the research: People who took the maximum dose of tirzepatide over 72 weeks lost an average of 21 percent of their body weight, according to data from clinical trials published in ...
About 82% of participants taking tirzepatide experienced 5% or greater weight loss. In comparison, only 66.5% of participants taking semaglutide achieved this level of weight loss. Which one to choose
A new study explores the reasons why tirzepatide, the once-weekly injection used to treat obesity and type 2 diabetes, is associated with greater weight loss in women than men.
Tirzepatide is an antidiabetic medication used for the treatment of type 2 diabetes [10] [13] [14] [15] and for weight loss. [11] [16] Tirzepatide is administered via subcutaneous injections (under the skin). [10] [13] It is sold under the brand name Mounjaro for diabetes treatment, [10] and Zepbound for weight loss and treatment of obstructive ...
As of 2022, there is no pathway for approval for drugs that reduce fat mass without 5 percent overall weight loss, even if they significantly improve metabolic health; neither is there one for drugs that help patients maintain weight loss although this can be more challenging than losing weight. [18]
For the efficacy estimand, tirzepatide led to a 15.7% (in a combined population of people with and without type 2 diabetes) body weight reduction compared to 2.2% for placebo.
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