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Download as PDF; Printable version; In other projects ... In physics and geosciences, the term spatial resolution refers to distance between ... spatial resolution is ...
The theoretical model was first proposed by Yuan in 2009, he developed an ultrasound-modulated fluorescence based on a fluorophore-quencher-labeled microbubble system which can control the fluorescent emission inside the ultrasound-focal zone to increase the spatial resolution and SNR o f the imaging. [3]
The spatial resolution of sensory-evoked CBV response can go down to cortical column (~100 μm). Temporally, the CBV impulse response function was measured to typically start at ~0.3 s and peak at ~1 s in response to ultrashort stimuli (300μs), which is much slower than the underlying electrical activity.
By combining the optical imaging with ultrasound, it is possible to achieve both high contrast and spatial resolution. [1] The photoacoustic Doppler flowmetry could use the power of photoacoustics to measure flow velocities that are usually inaccessible to pure light-based or ultrasound techniques.
Photoacoustic imaging or optoacoustic imaging is a biomedical imaging modality based on the photoacoustic effect.Non-ionizing laser pulses are delivered into biological tissues and part of the energy will be absorbed and converted into heat, leading to transient thermoelastic expansion and thus wideband (i.e. MHz) ultrasonic emission.
While OCT has fantastic spatial resolution (3.5 and 7 micrometer resolutions, axially and lateral respectively), its imaging depth is limited to the millimeter range (e.g. 2.5 mm). [7] DOT has fantastic penetration, on the scale of centimeters, but suffers from inferior resolution (~1cm). [8]
Ultrasound Localization Microscopy (ULM) is an advanced ultrasound imaging technique. By localizing microbubbles, ULM overcomes the physical limit of diffraction, achieving sub-wavelength level resolution and qualifying as a super-resolution technique. [1] [2] ULM is primarily utilized in vascular imaging.
This particular biomedical imaging modality is a combination of optical imaging, and ultrasound imaging. In other words, a photoacoustic (PA) image can be viewed as an ultrasound image in which its contrast depends on the optical properties, such as optical resolution of biomolecules like hemoglobin, water, melanin, lipids, and collagen.