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This side effect has been particularly associated with serotonergic antidepressants like SSRIs and SNRIs, but may be less with atypical antidepressants like bupropion, agomelatine, and vortioxetine. [ 77 ] [ 79 ] [ 80 ] Higher doses of antidepressants seem to be more likely to produce emotional blunting than lower doses. [ 77 ]
This side effect has been particularly associated with serotonergic antidepressants like SSRIs and SNRIs but may be less with atypical antidepressants like bupropion, agomelatine, and vortioxetine. [ 167 ] [ 173 ] [ 176 ] [ 177 ] Higher doses of antidepressants seem to be more likely to produce emotional blunting than lower doses. [ 167 ]
Also, currently available antidepressants all elicit undesirable side-effects, and new agents should be divested of the distressing side-effects of both first and second-generation antidepressants. [6] Another serious drawback of all antidepressants is the requirement for long-term administration prior to maximal therapeutic efficacy.
Some antidepressants, including commonly prescribed ones from the class known as SSRIs (selective serotonin reuptake inhibitors), can cause sexual side effects such as erectile dysfunction ...
A not-so-fun fact: Intimate dysfunction often occurs as a side effect of antidepressants. In men, the side effects of antidepressants result in reduced drive (low libido) or lowered desire ...
In clinical trials, the pills eased depression without the sexual side effects that can push some people to quit SSRIs. And there were no adverse effects on weight, blood pressure, heart rate, or ...
Many of these symptoms may be side effects of the drug or drug interaction causing excessive levels of serotonin rather than an effect of elevated serotonin itself. Tremor is a common side effect of MDMA's action on dopamine, whereas hyperreflexia is symptomatic of exposure to serotonin agonists.
Studies of SSRIs in patients with major psychiatric disorders prove that SSRIs are potentially associated with certain neurocognitive adverse effects such as anxiety, akathisia, hypomania, changes in mood, or suicidal thought. [30] [31] No study on the effects of SSRIs in men with PE has been done. McMahon's study in 2012 showed that dapoxetine ...