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Neisseria gonorrhoeae, also known as gonococcus (singular) or gonococci (plural), is a species of Gram-negative diplococci bacteria first isolated by Albert Neisser in 1879. [3] An obligate human pathogen, it primarily colonizes the mucosal lining of the urogenital tract; however, it is also capable of adhering to the mucosa of the nose, [ 4 ...
Neisseria is a large genus of bacteria that colonize the mucosal surfaces of many animals. Of the 11 species that colonize humans, only two are pathogens, N. meningitidis and N. gonorrhoeae. Neisseria species are Gram-negative bacteria included among the Pseudomonadota, a large group of Gram-negative forms.
Neisseria gonorrhoeae is a gram negative diplococcus (also referred to as "Gonococcus") and a pathogenic bacteria. [2] In 2019, there were 616,392 reported cases of gonorrhea in the United States, with an overall increased rate 5.7% from 2018 to 2019. [6]
If Gram-negative, oxidase-positive diplococci are visualized on direct Gram stain of urethral pus (male genital infection), no further testing is needed to establish the diagnosis of gonorrhea infection. [40] [41] However, direct Gram stain of cervical swabs is not useful because the N. gonorrhoeae organisms are less concentrated in these samples.
This genus, Neisseria, is divided into more than ten different species, but most of them are gram negative and coccoid. The gram-negative, coccoid species include: Neisseria cinerea, N. gonorrhoeae, N. polysaccharea, N. lactamica, N. meningitidis, N. mucosa, N. oralis and N. subflava. The most common of these species are the pathogenic N ...
The Neisseriaceae are a family [2] of Pseudomonadota, within the Neisseriales order of Betaproteobacteria.While many organisms in the family are mammalian commensals or part of the normal flora, the genus Neisseria includes two important human pathogens, specifically those responsible for gonorrhea (caused by N. gonorrhoeae) and many cases of meningitis ("meningococcal meningitis", caused by N ...
Medically-relevant gram-negative diplococci include the four types that cause a sexually transmitted disease (Neisseria gonorrhoeae [15]), a meningitis (Neisseria meningitidis [16]), and respiratory symptoms (Moraxella catarrhalis, [17] A coccobacillus Haemophilus influenzae is another medically relevant coccal type. [18]
Gram negative Neisseria gonorrhoeae and pus cells. Gram-negative bacteria generally possess a thin layer of peptidoglycan between two membranes (diderm). [26] Lipopolysaccharide (LPS) is the most abundant antigen on the cell surface of most gram-negative bacteria, contributing up to 80% of the outer membrane of E. coli and Salmonella. [27]
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