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Lasofoxifene, sold under the brand name Fablyn, is a nonsteroidal selective estrogen receptor modulator (SERM) which is marketed by Pfizer in Lithuania and Portugal for the prevention and treatment of osteoporosis and for the treatment of vaginal atrophy, [1] [2] and the result of an exclusive research collaboration with Ligand Pharmaceuticals (LGND).
Her major research focus over the last decade is the use of teriparatide, a bone building medication, in combination with antiresorptive agents, and in novel cyclic regimens, in the treatment of severe osteoporosis. Her research has focused on the causes of osteoporosis and how the female hormone estrogen and drugs called SERMS work to treat ...
Her research primarily focuses on metabolic bone disorders. This encompasses investigations into the epidemiology, pathophysiology, and treatment of osteoporosis, as well as the impact of hypovitaminosis D on musculoskeletal health. Additionally, she explores women's health issues and the utilization of densitometry measurements.
Steps that older adults can take to reduce their risk of falls and fractures include getting screened for osteoporosis, especially for women 65 and older, Rao said, and getting regular exercise.
Research shows the drug increases bone formation and decreases bone resorption in postmenopausal women with low bone density. Romosozumab was approved for medical use in Japan, the United States and the European Union in 2019. [7] [10] [11] The US Food and Drug Administration (FDA) considers it to be a first-in-class medication. [12]
In December 2024, the CHMP adopted a positive opinion, recommending the granting of a marketing authorization for the medicinal product Stoboclo, intended for the treatment of osteoporosis in women who have been through menopause, bone loss linked to hormone ablation in men at increased risk of fractures and bone loss associated with long-term ...
A new draft recommendation from the U.S. Task Force says taking vitamin D supplements with or without calcium does not prevent falls or fractures in older adults. kali9/Getty Images
Raloxifene is used for the treatment and prevention of osteoporosis in postmenopausal women. [11] It is used at a dosage of 60 mg/day for both the prevention and treatment of osteoporosis. [12] In the case of either osteoporosis prevention or treatment, supplemental calcium and vitamin D should be added to the diet if daily intake is inadequate ...
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