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Infectious mononucleosis (IM, mono), also known as glandular fever, is an infection usually caused by the Epstein–Barr virus (EBV). [2] [3] Most people are infected by the virus as children, when the disease produces few or no symptoms. [2] In young adults, the disease often results in fever, sore throat, enlarged lymph nodes in the neck, and ...
There are several forms of Epstein–Barr virus (EBV) infection. These include asymptomatic infections, the primary infection, infectious mononucleosis, and the progression of asymptomatic or primary infections to: 1) any one of various Epstein–Barr virus-associated lymphoproliferative diseases such as chronic active EBV infection, EBV+ hemophagocytic lymphohistiocytosis, Burkitt's lymphoma ...
See also Infectious mononucleosis and the other diseases listed in this section EBV causes infectious mononucleosis. [ 56 ] Children infected with EBV have few symptoms or can appear asymptomatic, but when infection is delayed to adolescence or adulthood, it can cause fatigue , fever , inflamed throat , swollen lymph nodes in the neck, enlarged ...
Epstein–Barr virus infectious mononucleosis (Mono) Diagnostic modalities for infectious mononucleosis include: Person's age, with highest risk at 10 to 30 years. Medical history, such as close contact with other people with infectious mononucleosis; Physical examination, including palpation of any enlarged lymph nodes in the neck, or enlarged ...
It has not been found to be useful for infectious mononucleosis due to Epstein-Barr virus. [18] Valaciclovir and acyclovir act by inhibiting viral DNA replication, but as of 2016 there was little evidence that they are effective against Epstein–Barr virus, they are expensive, they risk causing resistance to antiviral agents, and (in 1% to 10% ...
Heterophile antibodies are IgM antibodies with affinity for sheep and horse red blood cells. They appear during the first week of infectious mononucleosis symptoms, 3–4 weeks after infection and return to undetectable levels 3 to 6 months after infection. Heterophile antibody is a fairly specific but insensitive test for EBV.
Fever or chills. Cough. Shortness of breath or difficulty breathing. Sore throat. Congestion or runny nose. New loss of taste or smell. Fatigue. Muscle or body aches. Headache. Nausea or vomiting ...
This was recognized as a clinical syndrome in the 1800s consisting of fever, pharyngitis and adenopathy. The term glandular fever was first used in 1889 and the association with Epstein-Barr virus infection in the late 1960s. Sprunt and Evans described the characteristics of Epstein-Barr virus infectious mononucleosis in 1920.