Search results
Results from the WOW.Com Content Network
Radial glial cells, or radial glial progenitor cells (RGPs), are bipolar-shaped progenitor cells that are responsible for producing all of the neurons in the cerebral cortex. RGPs also produce certain lineages of glia , including astrocytes and oligodendrocytes .
Studies have shown that radial glia in the SGZ express nestin and Sox2, biomarkers associated with neural stem cells, and that isolated radial glia can generate new neurons in vitro. [8] Radial glial cells often divide asymmetrically, producing one new stem cell and one neuronal precursor cell per division. Thus, they have the capacity for self ...
In the mature brain, the cerebellum and retina retain characteristic radial glial cells. In the cerebellum, these are Bergmann glia , which regulate synaptic plasticity . In the retina, the radial Müller cell is the glial cell that spans the thickness of the retina and, in addition to astroglial cells, [ 16 ] participates in a bidirectional ...
Radial glial cells, also called radial glial progenitor cells, divide asymmetrically to produce a neuroblast and another radial glial cell that will re-enter the cell cycle. [5] [3] This mitosis occurs in the germinal neuroepithelium (or germinal zone), when a radial glial cell divides to produce the neuroblast. The neuroblast detaches from the ...
The protomap is a feature of the ventricular zone, which contains the principal cortical progenitor cells, known as radial glial cells. [2] [3] Through a process called 'cortical patterning', the protomap is patterned by a system of signaling centers in the embryo, which provide positional information and cell fate instructions.
Gliogenesis results in the formation of non-neuronal glia populations from neuronal cells. In this capacity, glial cells provide multiple functions to both the central nervous system (CNS) and the peripheral nervous system (PNS). Subsequent differentiation of glial cell populations results in function-specialized glial lineages.
The radial glial cells are disposed in planes perpendicular to the axes of ventricles. One of their processes abuts the pia mater , while the other is deeply buried in gray matter. Radial glia are mostly present during development, playing a role in neuron migration .
This page was last edited on 26 May 2011, at 20:01 (UTC).; Text is available under the Creative Commons Attribution-ShareAlike 4.0 License; additional terms may apply ...