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Alpha-gal syndrome (AGS), also known as alpha-gal allergy or mammalian meat allergy (MMA), [1] is a type of acquired allergy characterized by a delayed onset of symptoms (3–8 hours) after ingesting mammalian meat. The condition results from past exposure to certain tick bites and was first reported in 2002.
Here’s everything you need to know about alpha-gal syndrome
Alpha-gal syndrome is not triggered by poultry, seafood, or reptiles. The range of symptoms is vast; alpha-gal syndrome can cause hives, heartburn, nausea or vomiting, diarrhea, drops in blood ...
Alpha-gal syndrome on the rise One of the July 2023 CDC reports estimated that, from 2017 to 2022, there were more than 90,000 documented cases of suspected alpha-gal syndrome in the U.S.
Alpha-gal allergy - Alpha-gal syndrome is likely caused by a hypersensitivity reaction to the Alpha-gal (Galactose-alpha-1,3-galactose) sugar molecule introduced by ticks while feeding on a human host. The immune reaction can leave people with an allergy to red meat and other mammalian derived products.
Galactose-α-1,3-galactose, commonly known as alpha gal and the Galili antigen, is a carbohydrate found in most mammalian cell membranes. It is not found in catarrhines , [ 1 ] including humans, who have lost the GGTA1 gene.
What is alpha-gal syndrome? The lone star tick can cause an allergic reaction known as alpha-gal syndrome. The tick's saliva contains a sugar molecule called galactose-alpha-1,3-galactose (alpha-gal).
Pork–cat syndrome is an allergy to pork, usually after adolescence, that is related to cat allergy. Although first described in 1994, [1] [2] [3] it was first documented in the U.S. by Scott Commins and Thomas Platts-Mills during their research on alpha-gal allergy.