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Schizophrenia has been found to present cross-culturally, and it almost always has 0.1% prevalence in a given population, although some studies have cast doubts on this. It has been hypothesized that schizophrenia is unique to human beings and has existed for a long time. [1]
Given the high numbers of individuals diagnosed with schizophrenia (nearly 1% of modern-day populations), it is unlikely that the disorder has arisen solely from random mutations. [2] Instead it is believed that, despite its maladaptive nature, schizophrenia has been either selected for throughout the years or exists as a selective by-product.
Anti-psychiatrists agree that 'schizophrenia' represents a problem, and that many human beings have problems living in modern society. [ citation needed ] But they protest the notion that schizophrenia is a disease, and that people who have it are sick.
Schizophrenia affects around 0.3–0.7% of people at some point in their life. [19] [14] In areas of conflict this figure can rise to between 4.0 and 6.5%. [254] It occurs 1.4 times more frequently in males than females and typically appears earlier in men. [87] Worldwide, schizophrenia is the most common psychotic disorder. [56]
This is one of the main reasons that 40 percent of people with schizophrenia stop taking their medications within 18 months. And while antipsychotics can help schizophrenia’s “positive” symptoms, such as hallucinations, they have a minimal impact on the “negative” symptoms, which are arguably more devastating.
The quasi-dimensional model may be traced back to Bleuler [2] (the inventor of the term 'schizophrenia'), who commented on two types of continuity between normality and psychosis: that between the schizophrenic and their relatives, and that between the patient's premorbid and post-morbid personalities (i.e. their personality before and after ...
Recent developments in schizophrenia research, however, have targeted cognitive symptoms as some of the most debilitating and influential in patients' daily lives, and thus have become a larger target in animal models of schizophrenia. [1] Animals used as models for schizophrenia include rats, mice, and primates.
Schizophrenia is a debilitating and often misunderstood disorder that affects up to 1% of the world's population. [1] Although schizophrenia is a heavily studied disorder, it has remained largely impervious to scientific understanding; epigenetics offers a new avenue for research, understanding, and treatment.
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