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2. B cell - Wikipedia

   en.wikipedia.org/wiki/B_cell

   B cell activation occurs in the secondary lymphoid organs (SLOs), such as the spleen and lymph nodes. [1] After B cells mature in the bone marrow, they migrate through the blood to SLOs, which receive a constant supply of antigen through circulating lymph. [14] At the SLO, B cell activation begins when the B cell binds to an antigen via its BCR ...

3. Lymphatic system - Wikipedia

   en.wikipedia.org/wiki/Lymphatic_system

   A lymph node showing afferent and efferent lymphatic vessels Regional lymph nodes. A lymph node is an organized collection of lymphoid tissue, through which the lymph passes on its way back to the blood. Lymph nodes are located at intervals along the lymphatic system.

4. Lymph node - Wikipedia

   en.wikipedia.org/wiki/Lymph_node

   Each B cell produces different antibodies, and this process is driven in lymph nodes. B cells enter the bloodstream as "naive" cells produced in bone marrow. After entering a lymph node, they then enter a lymphoid follicle, where they multiply and divide, each producing a different antibody.

5. 5 Things You Should Know About DLBCL, the Most Common ... - AOL

   www.aol.com/5-things-know-dlbcl-most-130022299.html

   DLBCL is an aggressive type of B-cell NHL that grows rapidly in the lymph nodes and frequently involves the spleen, liver, bone marrow or other organs. 4 Although the disease can affect people of ...

6. Lymphopoiesis - Wikipedia

   en.wikipedia.org/wiki/Lymphopoiesis

   These B cells then leave the bone marrow and migrate via bloodstream and the lymph to peripheral lymphoid tissues, such as a spleen, lymph nodes, tonsils and mucosal tissues. Once in a secondary lymphoid organ the B cell can be introduced to an antigen that it is able to recognize. [citation needed]

7. Lymphocyte - Wikipedia

   en.wikipedia.org/wiki/Lymphocyte

   A lymphocyte is a type of white blood cell (leukocyte) in the immune system of most vertebrates. [1] Lymphocytes include T cells (for cell-mediated and cytotoxic adaptive immunity), B cells (for humoral, antibody-driven adaptive immunity), [2] [3] and innate lymphoid cells (ILCs; "innate T cell-like" cells involved in mucosal immunity and homeostasis), of which natural killer cells are an ...

8. Follicular dendritic cells - Wikipedia

   en.wikipedia.org/wiki/Follicular_dendritic_cells

   Follicular dendritic cells (FDC) are cells of the immune system found in primary and secondary lymph follicles (lymph nodes) of the B cell areas of the lymphoid tissue. [1] [2] [3] Unlike dendritic cells (DC), FDCs are not derived from the bone-marrow hematopoietic stem cell, but are of mesenchymal origin. [4]

9. Haematopoietic system - Wikipedia

   en.wikipedia.org/wiki/Haematopoietic_system

   As development progresses, blood formation occurs in the spleen, liver and lymph nodes. When bone marrow develops, it eventually assumes the task of forming most of the blood cells for the entire organism. [3] However, maturation, activation, and some proliferation of lymphoid cells occurs in the spleen, thymus, and lymph nodes. In children ...