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  2. The best kojic acid skin care products to brighten skin - AOL

    www.aol.com/news/best-kojic-acid-skin-care...

    This toner takes skin-brightening to the next level by pairing kojic acid with vitamin C — yet another tyrosinase inhibitor — as well as bearberry extract, a plant-based alternative to ...

  3. 4-Butylresorcinol - Wikipedia

    en.wikipedia.org/wiki/4-Butylresorcinol

    Hyperpigmentation is believed to be related to the enzyme tyrosinase which produces melanin. Among several chemicals known to inhibit tyrosinase production, such as hydroquinone, arbutin, and kojic acid, 4-butylresorcinol has been found to be the most powerful inhibitor by a wide margin.

  4. This Chronic Skin Condition Is A Common Cause Of Dark ... - AOL

    www.aol.com/chronic-skin-condition-common-cause...

    Your doctor may suggest taking a low dose of melatonin because it inhibits tyrosinase (an enzyme in our skin that helps produce melanin), reducing pigment production, says Dr. Charles ...

  5. α-Arbutin - Wikipedia

    en.wikipedia.org/wiki/Α-Arbutin

    It is more potent an inhibitor of tyrosinase than arbutin. [2] α-Arbutin directly inhibits the enzymatic activity of tyrosinase, which is essential for melanin synthesis. Tyrosinase catalyzes the first two steps in melanin production: the hydroxylation of tyrosine to l-DOPA and the oxidation of l-DOPA to dopaquinone.

  6. Tyrosinase - Wikipedia

    en.wikipedia.org/wiki/Tyrosinase

    Decreasing tyrosinase activity has been targeted for the improvement or prevention of conditions related to the hyperpigmentation of the skin, such as melasma and age spots. [ 22 ] Several polyphenols, including flavonoids or stilbenoid , substrate analogues, free radical scavengers, and copper chelators, have been known to inhibit tyrosinase ...

  7. Experts Agree: These Are the 11 Best Hyperpigmentation Serums

    www.aol.com/11-best-hyperpigmentation-serums...

    An effective hyperpigmentation treatment is not one-size-fits-all. However, good ingredients to look for in a hyperpigmentation serum include vitamin C, niacinamide, kojic acid, retinoids, azelaic ...

  8. Skin whitening - Wikipedia

    en.wikipedia.org/wiki/Skin_whitening

    Several skin whitening agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis. [ 41 ] Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1 ...

  9. 11 dermatologist-approved melasma treatments of 2023

    www.aol.com/news/11-dermatologist-approved...

    Shop the best melasma treatments and serums for hyperpigmentation. Expert-recommended products include La Roche Posay, Neutrogena, SkinCeuticals and more. 11 dermatologist-approved melasma ...

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