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Tranexamic acid, azelaic acid and vitamin C all function as tyrosinase inhibitors, meaning that, as with kojic acid, they prevent the formation of an enzyme that’s critical for the pigment ...
α-Arbutin's mechanism of action as a skin lightening agent is primarily through the competitive enzymatic inhibition of tyrosinase, leading to a decrease in melanin production without affecting the mRNA gene expression of tyrosinase. It is more potent an inhibitor of tyrosinase than arbutin.
Among several chemicals known to inhibit tyrosinase production, such as hydroquinone, arbutin, and kojic acid, 4-butylresorcinol has been found to be the most powerful inhibitor by a wide margin. [ 1 ] 4-Butylresorcinol can be used in the synthesis of Tetrahydrocannabutol .
Several skin whitening agents, including tyrosinase inhibitors, have been found to cause an increase in the expression of tyrosinase, which by itself would increase melanin synthesis. [ 41 ] Microphthalmia-associated transcription factor (MITF) is the master transcription factor that controls the expression of TYR, TRP1, and TRP2, MART1 ...
In short, melasma is a chronic skin condition that appears as darkened areas on the face due to an overproduction of melanin, says Gina Charles, MO, a family physician specializing in skincare. It ...
It may sound like chemistry soup, but, according to Dr. Diana Howard, vice president of research and development and global education for Dermalogica, niacinamide is the next BIG skin-care ...
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