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Hypercholesterolemia, also called high cholesterol, is the presence of high levels of cholesterol in the blood. [1] It is a form of hyperlipidemia (high levels of lipids in the blood), hyperlipoproteinemia (high levels of lipoproteins in the blood), and dyslipidemia (any abnormalities of lipid and lipoprotein levels in the blood). [1]
For example, some may lower low density lipoprotein (LDL) levels more so than others, while others may preferentially increase high density lipoprotein (HDL). Clinically, the choice of an agent depends on the patient's cholesterol profile , cardiovascular risk , and the liver and kidney functions of the patient, evaluated against the balancing ...
Other lipoprotein levels are typically within the normal reference range or slightly increased. [28] Treatment include diet control, fibrates and niacins. Although statins are typically the first line treatment for hyperlipidemias, fibrates are actually better at reducing elevated triglyceride levels and are considered first line. [29]
Lipoprotein: Hyperlipoproteinemia: lipoproteins (usually LDL unless otherwise specified) Honemia: chylomicrons; Hypolipoproteinemia: lipoproteins. Abetalipoproteinemia: beta lipoproteins; Tangier disease: Tangier disease is an inherited disorder characterized by significantly reduced levels of high-density lipoprotein (HDL) in the blood. Both
High-density lipoprotein (HDL) is one of the five major groups of lipoproteins. [1] Lipoproteins are complex particles composed of multiple proteins which transport all fat molecules around the body within the water outside cells. They are typically composed of 80–100 proteins per particle (organized by one, two or three ApoA). HDL particles ...
According to a solid collection of scientific evidence, high levels of lipoprotein(a)—also known as Lp(a), pronounced “L-P-little-a”—leads to an increased risk of atherosclerotic ...
“The highest levels of lipoprotein (a) in this study weren’t even high enough to reach the clinical threshold at which a patient would be treated,” he said. “It tends to underestimate the ...
[21] [22] [23] Risk factors for coronary heart disease included abnormal lipid levels in the blood, diabetes mellitus, high blood pressure, and smoking. [22] They recommended selective use of low-to-moderate doses statins in the same adults who have a calculated 10-year cardiovascular disease event risk of 7.5–10% or greater. [ 22 ]
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