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  2. Destination therapy - Wikipedia

    en.wikipedia.org/wiki/Destination_therapy

    Ventricular assist devices require open-heart surgery for implantation. An incision is made through the breastbone to expose the heart. Heparin will be given to keep the patients blood from clotting. The blood is rerouted to a heart-lung machine that will pump and oxygenate blood. A pocket for the LVAD is formed in the abdominal wall.

  3. Ventricular assist device - Wikipedia

    en.wikipedia.org/wiki/Ventricular_assist_device

    The first left ventricular assist device (LVAD) system was created by Domingo Liotta at Baylor College of Medicine in Houston in 1962. The first LVAD was implanted in 1963 by Liotta and E. Stanley Crawford. The first successful implantation of an LVAD was completed in 1966 by Liotta along with Dr. Michael E. DeBakey.

  4. Bridge therapy - Wikipedia

    en.wikipedia.org/wiki/Bridge_therapy

    For example, a left ventricular assist device (LVAD) often serves as a bridge to heart transplant, [1] locoregional therapy (such as radiofrequency ablation) for hepatocellular carcinoma can serve as a bridge to liver transplant, [2] and extracorporeal membrane oxygenation (ECMO) or lung volume reduction surgery (LVRS) can serve as a bridge to ...

  5. Pump thrombosis - Wikipedia

    en.wikipedia.org/wiki/Pump_thrombosis

    Pump thrombosis is defined as a specific case of a major device malfunction. In turn, device malfunction is as defined by Interagency Registry for Mechanically Assisted Circulatory Support (INTERMACS) as a failure of one or more of the components of the mechanical circulatory support systems which either directly causes or could potentially induce a state of inadequate circulatory support (low ...

  6. Thoratec - Wikipedia

    en.wikipedia.org/wiki/Thoratec

    With the 2001 Thermo Cardiosystems merger, Thoratec acquired the HeartMate Left Ventricular Assist System, an implanted VAD for end-stage heart patients. A landmark three-year study of 129 patients at 22 major medical centers, called REMATCH (Randomized Evaluation of Mechanical Assistance for the Treatment of Congestive Heart Failure) and published in November 2001, found that the HeartMate VE ...

  7. Pedro J. del Nido - Wikipedia

    en.wikipedia.org/wiki/Pedro_J._del_Nido

    The myocardial contraction-relaxation cycle, similar to other muscle, is closely reliant upon the intracellular calcium concentration. Magnesium is a calcium channel blocker, so its use in hypothermic cardioplegia improves ventricular recovery when coupled with a low calcium level.

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  9. Jack Copeland (surgeon) - Wikipedia

    en.wikipedia.org/wiki/Jack_Copeland_(surgeon)

    Jack Greene Copeland (born 1942) is an American cardiothoracic surgeon, who has established procedures in heart transplantation including repeat heart transplantation, the implantation of total artificial hearts (TAH) to bridge the time to heart transplant, innovations in left ventricular assist devices (LVAD) and the technique of "piggybacking" a second heart (heterotopic heart transplant) in ...

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