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Hypertrophic cardiomyopathy (HCM, or HOCM when obstructive) is a condition in which muscle tissues of the heart become thickened without an obvious cause. [8] The parts of the heart most commonly affected are the interventricular septum and the ventricles. [10]
Hypertrophic cardiomyopathy screening is an assessment and testing to detect hypertrophic cardiomyopathy (HCM). [ 1 ] [ 2 ] It is a way of identifying HCM in immediate relatives of family members diagnosed with HCM, and athletes as part of a sports medical . [ 3 ]
In 2015 cardiomyopathy and myocarditis affected 2.5 million people. [6] Hypertrophic cardiomyopathy affects about 1 in 500 people while dilated cardiomyopathy affects 1 in 2,500. [3] [10] They resulted in 354,000 deaths up from 294,000 in 1990. [7] [11] Arrhythmogenic right ventricular dysplasia is more common in young people. [2]
But the last 20 years have witnessed a sea change in the condition’s management—a change that has led to an estimated 10-fold decrease in deaths. “Hypertrophic cardiomyopathy has this ...
Heart conditions may be more often associated with older individuals, but you might be surprised to learn hypertrophic cardiomyopathy is the most common condition responsible for sudden cardiac ...
Alcohol septal ablation (ASA) is a minimally invasive heart procedure to treat hypertrophic cardiomyopathy (HCM). [1]It is a percutaneous, minimally invasive procedure performed by an interventional cardiologist to relieve symptoms and improve functional status in eligible patients with severely symptomatic HCM who meet strict clinical, anatomic and physiologic selection criteria.
Aficamten (CK-274) is a cardiac myosin inhibitor [1] developed by Cytokinetics for the treatment of obstructive hypertrophic cardiomyopathy. [2] [3] [4] References
Mavacamten, sold under the brand name Camzyos, is a medication used to treat obstructive hypertrophic cardiomyopathy. [8] [9] Mavacamten is a small-molecule allosteric [10] and cardiac myosin inhibitor. [8] It was developed by MyoKardia, a subsidiary of Bristol Myers Squibb. [11]
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