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The rifamycins have a unique mechanism of action, selectively inhibiting bacterial DNA-dependent RNA polymerase, and show no cross-resistance with other antibiotics in clinical use. However, despite their activity against bacteria resistant to other antibiotics , the rifamycins themselves suffer from a rather high frequency of resistance.
Management of tuberculosis refers to techniques and procedures utilized for treating tuberculosis (TB), or simply a treatment plan for TB.. The medical standard for active TB is a short course treatment involving a combination of isoniazid, rifampicin (also known as Rifampin), pyrazinamide, and ethambutol for the first two months.
Rifampicin can reduce the efficacy of birth control pills or other hormonal contraception by its induction of the cytochrome P450 system, to the extent that unintended pregnancies have occurred in women who use oral contraceptives and took rifampicin even for very short courses (for example, as prophylaxis against exposure to bacterial meningitis).
It is an automated diagnostic test that can identify Mycobacterium tuberculosis (MTB) DNA and resistance to rifampicin (RIF). It was co-developed by the laboratory of Professor David Alland at the University of Medicine and Dentistry of New Jersey (UMDNJ), [ 1 ] Cepheid Inc. and Foundation for Innovative New Diagnostics , with additional ...
In some literature articles, the terms "mechanism of action" and "mode of action" are used interchangeably, typically referring to the way in which the drug interacts and produces a medical effect. However, in actuality, a mode of action describes functional or anatomical changes, at the cellular level, resulting from the exposure of a living ...
People loved the orange cat's reaction to the tree and had a lot to say about Abram's video. @Jen got more than 300 likes when she pointed out, "He's the angel on top of his tree!" @Austin ...
Credit - Denis Novikov—iStock/Getty Images. I f you’ve been scrolling too long on social media, you might be suffering from “brain rot,” the word of 2024, per the publisher of the Oxford ...
3. Bojangles. Bojangles is a game of highs and lows. I hate some things (read: fries) and adore others (read: sweet potato pie) and the new nuggets, or, “Bo Bites” as they are called, really ...