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Penicillin became an important part of the Allied war effort in the Second World War, saving the lives of thousands of soldiers. Fleming, Florey and Chain shared the 1945 Nobel Prize in Physiology or Medicine for its discovery and development.
The drug's success in saving soldiers in World War II who had been dying from infected wounds resulted in Fleming, Florey and Chain jointly winning the Nobel Prize in Medicine in 1945. [20] Griseofulvin is an antifungal drug and a potential chemotherapeutic agent [21] that was discovered in P. griseofulvum. [22]
Fleming's discovery of penicillin changed the world of modern medicine by introducing the age of useful antibiotics; penicillin has saved, and is still saving, millions of people around the world. [81] The laboratory at St Mary's Hospital where Fleming discovered penicillin is home to the Fleming Museum, a popular London attraction.
Following the U.S. entry into World War II, Ingram joined the Army Medical Corps and was stationed at Billings General Hospital in Indianapolis, Indiana, from July 1 to September 1, 1942, and Bushnell General Hospital in Brigham, Utah, where he was among a select group of doctors to administer penicillin for the first time to U.S. patients.
It has been reported that infection by this bacterium of the wounds of soldiers in the American Civil War at the Battle of Shiloh caused the wounds to glow, and that this aided the survival of the soldiers due to the production of antibiotics by P. luminescens. [5] [6] This led to the phenomenon's nickname "Angel's Glow." [7]
During World War II, the United Kingdom and the United States worked together to find a method of mass-producing penicillin, [5] a derivative of the Penicillium mold, which had the potential to save many lives during the war since it could treat infections common in injured soldiers. Although penicillin could be isolated from the mold in a ...
Glass phial of British Standard penicillin. The history of penicillin follows observations and discoveries of evidence of antibiotic activity of the mould Penicillium that led to the development of penicillins that became the first widely used antibiotics. Following the production of a relatively pure compound in 1942, penicillin was the first ...
Since the early 20th century, research into the development of viable therapeutic antibiotics had also been underway, and by 1942, the antibiotic penicillin G had been successfully purified and saw use during the Second World War. The drug proved to be extraordinarily effective in the treatment of injured Allied soldiers whose wounds had become ...