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There was, and still is, a lot of speculation about what caused Beethoven's hearing loss. As with most medical conditions, there can be influences from genetic and environmental factors.
Usher syndrome, also known as Hallgren syndrome, Usher–Hallgren syndrome, retinitis pigmentosa–dysacusis syndrome or dystrophia retinae dysacusis syndrome, [1] is a rare genetic disorder caused by a mutation in any one of at least 11 genes resulting in a combination of hearing loss and visual impairment.
An analysis of locks of Ludwig van Beethoven’s hair suggest he had lead poisoning. It may have contributed to chronic ailments, deafness and — ultimately — his demise. ... But the results ...
Many causes of autism, including environmental and genetic factors, have been recognized or proposed, but understanding of the theory of causation of autism is incomplete. [1] Attempts have been made to incorporate the known genetic and environmental causes into a comprehensive causative framework. [ 2 ]
Waardenburg syndrome has multiple different types with some variations in symptoms, and symptoms can vary among those with the same type. The two features consistent across all types of Waardenburg syndrome are some degree of congenital sensorineural hearing loss and some degree of pigmentation deficiencies, most consistently in the eyes. [11]
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The link between NSAIDs and hearing loss tends to be greater in women, especially those who take ibuprofen six or more times a week. [36] Others may cause permanent hearing loss. [37] The most important group is the aminoglycosides (main member gentamicin) and platinum based chemotherapeutics such as cisplatin and carboplatin. [38] [39]
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