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The LAD gives off two types of branches: septals and diagonals. Septals originate from the LAD at 90 degrees to the surface of the heart, perforating and supplying the anterior 2/3 of the interventricular septum. Diagonals run along the surface of the heart and supply the lateral wall of the left ventricle and the anterolateral papillary muscle.
Normally, the blockage should affect approximately 70% of the artery for symptoms to become noticeable. [3] Symptoms can be less severe during gradual narrowing, as this allows time for the widening of existing vessels and the formation of new ones ( collateral vessels ), allowing blood to still reach the area.
Aortic stenosis is most commonly caused by age-related progressive calcific aortic valve disease (CAVD) (>50% of cases), with a mean age of 65 to 70 years. CAVD is the build-up of calcium on the cusps of the valve, and this calcification causes hardening and stenosis of the valve. [ 22 ]
Woman of 70 years old with hypertension and dyslipidemia. Microphotography of arterial wall with calcified (violet color) atherosclerotic plaque ( hematoxylin and eosin stain) Areas of severe narrowing, stenosis , detectable by angiography , and to a lesser extent " stress testing " have long been the focus of human diagnostic techniques for ...
Wellens' syndrome is an electrocardiographic manifestation of critical proximal left anterior descending (LAD) coronary artery stenosis in people with unstable angina. Originally thought of as two separate types, A and B, it is now considered an evolving wave form, initially of biphasic T wave inversions and later becoming symmetrical, often ...
Angina may present typically with classic symptoms or atypically with symptoms less often associated with heart disease. [19] Atypical presentations are more common in women, diabetics, and elderly individuals. [8] Angina may be stable or unstable. Unstable angina is most often associated with emergent, acute coronary syndromes. [20]
The study, which involved 106 peri- and postmenopausal women and was presented at the Endocrine Society’s annual meeting in May, indicates women should self-monitor their vasomotor symptoms and ...
Aortic dissection affects an estimated 2.0–3.5 people per every 100,000 every year. Studies from Sweden suggest that the incidence of aortic dissection may be rising. [46] Men are more commonly affected than women: 65% of all people with aortic dissection are male. The mean age at diagnosis is 63 years. [25]
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